Results 71 to 80 of about 4,503,165 (306)

Estimation for the bivariate negative binomial distribution

open access: yesJournal of Statistical Computation and Simulation, 1985
Subrahmaniam and Subrahmaniam (1973) have considered several estimation procedures for the parameters of the bivariate negative binomial distribution. In this paper even-point estimators are examined and relative comparisons with maximum likelihood, moment and zero-zero cell frequency estimators are given.
Loukas, S., Papageorgiou, H.
openaire   +3 more sources

Overcoming Artificial Structures in Resolution‐Enhanced Hi‐C Data by Signal Decomposition and Multi‐Scale Attention

open access: yesAdvanced Science, EarlyView.
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li   +6 more
wiley   +1 more source

Single‐Cell Dissection of Microglial Dysfunction in Diabetes‐Associated Neurodegenerative Vulnerability

open access: yesAdvanced Science, EarlyView.
Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang   +6 more
wiley   +1 more source

Weighted inequalities and negative binomials

open access: yesAdvances in Applied Mathematics, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

open access: yesAdvanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch   +6 more
wiley   +1 more source

Bounds on Negative Binomial Approximation to Call Function

open access: yesRevstat Statistical Journal
In this paper, we develop Stein's method for negative binomial distribution using call function defined by fz(k) = (k - z)+ = max{k - z, 0}, for k ≥ 0 and z ≥ 0.
Amit N. Kumar
doaj   +1 more source

Generalized Binomial Trees [PDF]

open access: yes
We consider the problem of consistently pricing new options given the prices of related options on the same stock. The Black-Scholes formula and standard binomial trees can only accommodate one related European option which then effectively specifies the
Jackwerth, Jens Carsten
core  

Hurdle Negative Binomial model estimation results.

open access: yes, 2016
Hurdle Negative Binomial model estimation results.
Tesfaye Alemayehu Gebremedhin (3394610)   +1 more
core   +1 more source

DyProL: Dynamic Ensemble Representation Learning for Protein–Nucleic Acid Binding Site Prediction

open access: yesAdvanced Science, EarlyView.
Protein function is represented as a dynamic conformational ensemble rather than a single static structure. A multi‐conformation geometric attention framework aligns, clusters, and learns representative states to capture residue‐ and ensemble‐level signals. Integrating structural dynamics improves interpretable protein‐NA binding prediction and reveals
Pengpai Li   +3 more
wiley   +1 more source

Constructing Arbitrage-free Binomial Models [PDF]

open access: yes, 2004
Wöster C. Constructing Arbitrage-free Binomial Models. Discussion paper / Fakultät für Wirtschaftswissenschaften, Universität Bielefeld. Bielefeld: Universität Bielefeld; 2004.In the past decades several versions of the binomial model for option pricing,
Wöster, Christoph
core  

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