Results 81 to 90 of about 377,610 (328)

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello, Rui Xiao, Xuemei Zhang, Jahan Jazayeri, Irit R. Rasooly, Pamela F. Weiss   +5 more
wiley   +1 more source

Effects of the Detection Efficiency on Multiplicity Distributions

, 2013
In this paper we investigate how a finite detection efficiency affects three popular multiplicity distributions, namely the Poisson, the Binomial and the Negative Binomial distributions.
Tang, A., Wang, G.
core   +1 more source

Determination of point estimates of negative binomial distribution parameters

Vojnotehnički Glasnik, 1999
A method for determining point estimates of c and p parameters of the negative binomial distribution has been presented in the paper. This is a method of moments because the estimation of these parameters is based on the mean value m and the standard ...
Dragoljub M. Brkić
doaj   +1 more source

Deterministic Detection of Single Ion Implantation

Advanced Engineering Materials, EarlyView.
Focused ion beam implantation with high detection efficiencies will enable the rapid and scalable fabrication of advanced spin‐based technologies such as qubits. This work presents the detection efficiencies of a wide range of ions implanted into solid‐state hosts, with efficiencies of >90% recorded for ion species and substrate combinations of ...
Mason Adshead, Lok Kan Wan, Maddison Coke, Janet Jacobs, Nicholas F. L. Collins, Mark C. Rosamond, Richard J. Curry   +6 more
wiley   +1 more source

A Poisson Mixed Model with Nonnormal Random Effect Distribution

, 2011
We propose in this paper a random intercept Poisson model in which the random effect distribution is assumed to follow a generalized log-gamma (GLG) distribution.
de Castro, Mario, Fabio, Lizandra C., Paula, Gilberto A.   +2 more
core   +1 more source

Negative Binomial Mixed Models for Analyzing Longitudinal Microbiome Data

Frontiers in Microbiology, 2018
The metagenomics sequencing data provide valuable resources for investigating the associations between the microbiome and host environmental/clinical factors and the dynamic changes of microbial abundance over time.
Xinyan Zhang, Yu-Fang Pei, Lei Zhang, Boyi Guo, Amanda H. Pendegraft, Wenzhuo Zhuang, Nengjun Yi   +6 more
doaj   +1 more source

Correlated Charge Transport in an Organic Coulomb Glass

Advanced Materials, EarlyView.
ABSTRACT Advances in the development of organic field‐effect transistors (OFETs), electrically gated organic semiconductors (EGOFETs), and organic electrochemical transistors (OECTs) allow for the operation of these devices at very high charge‐carrier densities, where Coulomb interactions between carriers can be expected to become significant.
Magdalena Sophie Dörfler, Heinz Bässler, Harald Oberhofer, Anna Köhler   +3 more
wiley   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

New robust estimators for the fixed effects negative binomial model: a simulation and real-world applications to European panel data

Frontiers in Applied Mathematics and Statistics
This study introduces a more flexible approach by employing the fixed effects negative binomial model to address challenges associated with outliers and dispersion.
Mohamed R. Abonazel, Ehab Ebrahim Mohamed Ebrahim, Elsayed G. Ahmed, Amera M. El-Masry   +3 more
doaj   +1 more source