Results 81 to 90 of about 4,503,165 (306)

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

open access: yesAdvanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao   +20 more
wiley   +1 more source

The negative binomial distribution [PDF]

open access: yes, 1956
Recent studies on biological data which vary somewhat from Poisson description have brought the negative binomial distribution into greater prominence.
Kaller, Cecil Louis
core  

The negative binomial GAM model statistics diagnosis.

open access: yes, 2015
The negative binomial GAM model statistics diagnosis.
Yujie Meng (818895)   +6 more
core   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

Negative Binomial Mixed Models for Analyzing Longitudinal Microbiome Data

open access: yesFrontiers in Microbiology, 2018
The metagenomics sequencing data provide valuable resources for investigating the associations between the microbiome and host environmental/clinical factors and the dynamic changes of microbial abundance over time.
Xinyan Zhang   +6 more
doaj   +1 more source

Multivariate negative binomial regression results–neighbourhood perceptions.

open access: yes, 2018
Multivariate negative binomial regression results–neighbourhood perceptions.
Alison Dias (6029660)   +4 more
core   +1 more source

The q-Binomial Coefficient for Negative Arguments and Some q-Binomial Summation Identities [PDF]

open access: yes, 2023
Using a property of the q-shifted factorial, an identity for q-binomial coefficients is proved, which is used to derive the formulas for the q-binomial coefficient for negative arguments.
Kronenburg, M. J.
core  

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

open access: yesAdvanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan   +13 more
wiley   +1 more source

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

open access: yesAdvanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning   +20 more
wiley   +1 more source

New robust estimators for the fixed effects negative binomial model: a simulation and real-world applications to European panel data

open access: yesFrontiers in Applied Mathematics and Statistics
This study introduces a more flexible approach by employing the fixed effects negative binomial model to address challenges associated with outliers and dispersion.
Mohamed R. Abonazel   +3 more
doaj   +1 more source

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