Results 31 to 40 of about 106,499 (262)
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
On intervened negative binomial distribution and some of its properties
Statistica, 2013 Here we develop a new class of discrete distribution namely intervened negative binomial distribution and derive its probability generating function, mean, variance and an expression for its factorial moments.
C. Satheesh Kumar, S. Sreejakumari
doaj +1 more source
New bounds on Poisson approximation to the distribution of a sum of negative binomial random variables [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2018 The Stein-Chen method is usedto give new bounds, non-uniform bounds, for the distances between the distribution of a sum of independent negative binomial random variables and a Poisson distribution with mean, where ri and pi = 1-qi are parameters of ...
Kanint Teerapabolarn
doaj +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Modeling citrus huanglongbing data using a zero-inflated negative binomial distribution
Acta Scientiarum. Agronomy, 2016 Zero-inflated data from field experiments can be problematic, as these data require the use of specific statistical models during the analysis process. This study utilized the zero-inflated negative binomial (ZINB) model with the log- and logistic-link ...
Eudmar Paiva de Almeida +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
The Marshall-Olkin Weibull Truncated Negative Binomial Distribution and its Applications
Statistica, 2019 The Weibull distribution is one of the widely known lifetime distribution that has been extensively used for modelling data in reliability and survival analysis.
Bindu Krishnan, Dais George
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis +77 more
wiley +1 more source