Results 101 to 110 of about 594,285 (313)

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

ANALYTICAL APPROACH OF GENERALIZED LINEAR MODELS FOR HANDLING OVERDISPERSION IN POVERTY DATA OF INDONESIA

Barekeng
Poverty is one of the complex phenomena that occurs in Indonesia. Various socio-economic variables in Indonesia influence poverty, which we can mathematically model using the Generalized Linear Model (GLM) framework. In this study, we modeled data on the
Restu Arisanti, Resa Septiani Pontoh, Sri Winarni, Fellita Odelia Wibowo, Hanifah Khairunnisa, Raissheva Andika Pratama   +5 more
doaj   +1 more source

NEGATIVE BINOMIAL REGRESSION METHODS TO ANALYZE FACTORS AFFECTING CHILD MORTALITY RATES IN WEST JAVA [PDF]

, 2015
Data on the number of child mortality cases are discrete data (count) which are usually analyzed with Poisson regression. The characteristics of the Poisson regression mean and variance must be the same, whereas in fact the count data is often becoming ...
Anang Kurnia, ., Farit M. Afendi, ., Hadiyatul Fitriyah, .   +2 more
core  

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that preces the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Scale-dependence of the Negative Binomial Pseudo-Maximum Likelihood Estimator [PDF]

Following Santos Silva and Tenreyro (2006), various studies have used the Poisson Pseudo-Maximum Likelihood to estimate gravity specifications of trade flows and non-count data models more generally.
Clément Bosquet, Hervé Boulhol
core  

Fast Bayesian Variable Selection in Binomial and Negative Binomial Regression

, 2021
18 pages; this work is superseded by arXiv:2208 ...
openaire   +2 more sources

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Parameter Estimation of Mixed Geographically Weighted Bivariate Zero-Inflated Negative Binomial Regression Model

Jambura Journal of Mathematics
The Bivariate Zero-Inflated Negative Binomial (BZINBR) regression model is commonly used to analyze two correlated count response variables characterized by overdispersion and excess zeros.
Mawadah Putri Islamiati, Purhadi Purhadi, Wibawati Wibawati   +2 more
doaj   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Robust Negative Binomial Regression via the Kibria–Lukman Strategy: Methodology and Application

Mathematics
Count regression models, particularly negative binomial regression (NBR), are widely used in various fields, including biometrics, ecology, and insurance.
Adewale F. Lukman, Olayan Albalawi, Mohammad Arashi, Jeza Allohibi, Abdulmajeed Atiah Alharbi, Rasha A. Farghali   +5 more
doaj   +1 more source