Results 91 to 100 of about 6,102,677 (302)
Advanced Science, EarlyView.Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
Parameters and model fitness statistics for multilevel negative binomial regression analysis.
, 2022 Parameters and model fitness statistics for multilevel negative binomial regression analysis.
Fetene Getnet Gebeyehu (14304807) +3 more
core +1 more source
Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis
Advanced Science, EarlyView.CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan +13 more
wiley +1 more source
Towards a Compositional Framework for Describing Human Phenotypes
Advanced Science, EarlyView.The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu +11 more
wiley +1 more source
Negative binomial Regression analysis: Participant characteristics and consultation behaviour.
, 2016 Negative binomial Regression analysis: Participant characteristics and consultation behaviour.
Carol Rivas (3332769) +7 more
core +1 more source
Path model for Study 2 (parameter estimates based on negative binomial regression).
, 2023 Path model for Study 2 (parameter estimates based on negative binomial regression).
Marius van Dijke (36225) +1 more
core +1 more source
Advanced Science, EarlyView.Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng +15 more
wiley +1 more source
BarekengPoverty is one of the complex phenomena that occurs in Indonesia. Various socio-economic variables in Indonesia influence poverty, which we can mathematically model using the Generalized Linear Model (GLM) framework. In this study, we modeled data on the
Restu Arisanti +5 more
doaj +1 more source
Advanced Science, EarlyView.KFO‐Atlas reveals how real‐world aromas are organized as structured mixtures rather than individual molecules. Building on these principles, KFO‐Gen, a generative AI framework, designs perceptually valid aroma formulations and reconstructs meat‐like aromas exclusively from plant‐derived odorants, providing a foundation for mixture‐level studies and AI ...
Jingzhi Zhang +5 more
wiley +1 more source
Fast Bayesian Variable Selection in Binomial and Negative Binomial Regression
, 2021 18 pages; this work is superseded by arXiv:2208 ...
openaire +2 more sources