Results 71 to 80 of about 6,102,677 (302)
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez +12 more
wiley +1 more source
Linear mean-variance negative binomial models for analysis of orange tissue-culture data [PDF]
Negative binomial maximum likelihood regression models are commonly used to analyze overdispersed Poisson data. There are various forms of the negative binomial model with different mean-variance relationships, however, the most generally used are those ...
Naratip Jansakul, John P. Hinde
doaj
Multivariate negative binomial regression results–perceived community connections.
Multivariate negative binomial regression results–perceived community connections.
Alison Dias (6029660) +4 more
core +1 more source
Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang +6 more
wiley +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
ANALISIS FAKTOR PENYEBAB PENYAKIT TBC DI JAWA BARAT MENGGUNAKAN REGRESI BINOMIAL NEGATIF
The realization of "Indonesia Emas 2045" is significantly determined by the current Golden Generation. It is expected that this generation possesses high competence, quality, and innovation.
Humaira Zeanova +3 more
doaj +1 more source
Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li +9 more
wiley +1 more source
Effect of inclusive growth on terrorism in Sub-Saharan Africa
The objective of this study is to analyse the effect of inclusive growth on terrorism using a sample of 33 Sub-Saharan African countries over the period 1996–2020.
Adama Sawadogo +2 more
doaj +1 more source
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao +12 more
wiley +1 more source
The number of poor people is an example of discrete or count data. One commonly used regression model for count responses is the Negative Binomial regression.
Vera Maya Santi +2 more
doaj +1 more source

