Results 231 to 240 of about 3,656,879 (280)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Disrupted functional connectivity during stroke recovery revealed via bedside optical neuroimaging. [PDF]

Neurophotonics
Bergonzi KM, Burke BA, Fogarty M, Sherafati A, Burns-Yocum TM, Ferradal SL, Palanca BJA, Dhar R, Kumar G, Lee JM, Culver JP, Eggebrecht AT.   +11 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Examining the Roles of Psychological Inflexibility and Distress Tolerance on Cigarette Dependence and Binge Drinking among Individuals who Co-use Cannabis for Therapeutic Purposes. [PDF]

Int J Ment Health Addict
Agterberg S, Bridgeman MB, Billingsley B, Rosen RL, O'Kane TW, Steinberg ML.   +5 more
europepmc   +1 more source

Childhood cancer survival in Africa, Asia, Latin America and the Caribbean, during 2008-2017 (SURVCAN-3): a population-based benchmarking study of 16 821 children. [PDF]

J Natl Cancer Inst
Daltveit DS, Morgan E, Bardot A, Steliarova-Foucher E, Damie A, Hagenimana M, Khoubila N, Moreno F, Soerjomataram I.   +8 more
europepmc   +1 more source

Reproducibility of Serum Androgen Concentrations by Liquid Chromatography Mass Spectrometry in Healthy Male and Female Athletes. [PDF]

Drug Test Anal
Handelsman DJ, Bermon S.
europepmc   +1 more source

Risk factors for myocarditis hospitalization and recurrence: a state-wide retrospective observational study. [PDF]

Eur Heart J Open
Kwan TN, Kwan G, Brieger D, Chow V, Kritharides L, Ng ACC.   +5 more
europepmc   +1 more source

A combined ex vivo fundus imaging-histology protocol for clinicopathological validation of human donor eyes with limited medical history. [PDF]

Sci Rep
Vijay Singh SH, Yeap W, Too LK, Allende A, Hall G, Hunyor A, Madigan MC, Merani R, Ortiz J, Rodriguez M, Wong J, Invernizzi A, Killingsworth M, Pye V, Mehta H, Petsoglou C, Cherepanoff S.   +16 more
europepmc   +1 more source