Results 121 to 130 of about 7,354,206 (251)

Dynamic Density Forecasts for Multivariate Asset Returns [PDF]

We propose a simple and flexible framework for forecasting the joint density of asset returns. The multinormal distribution is augmented with a polynomial in (time-varying) non-central co-moments of assets.
Evarist Stoja, Arnold Polanski
core  

Drivers of natural regeneration seedling dynamics in a Larix gmelinii var. principis-rupprechtii artificial forest

Scientific Reports
Seedling dynamics are crucial for forest regeneration and species coexistence. Understanding the factors influencing seedling survival rate provides insights into improving natural regeneration.
Weiwen Zhao, Yanjun Sun
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Negative density dependence promotes persistence of a globally rare yet locally abundant plant species Oenothera coloradensis

Identifying the mechanisms underlying the persistence of rare species has long been a motivating question for ecologists. Classical theory implies that community dynamics should be driven by common species, and that natural selection should not allow ...
Heidel, Bonnie, Laughlin, Daniel C., Stears, Alice E., Salguero-Gómez, Roberto, Paniw, María   +4 more
core   +1 more source

Multifaceted effects of variable biotic interactions on population stability in complex interaction webs

Communications Biology
Recent studies have revealed that biotic interactions in ecological communities vary over time, possibly mediating community responses to anthropogenic disturbances.
Koya Hashimoto, Daisuke Hayasaka, Yuji Eguchi, Yugo Seko, Ji Cai, Kenta Suzuki, Koichi Goka, Taku Kadoya   +7 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Relation between mean group size and population density for female (black) and male (gray) elk in Riding Mountain National Park (2002–2005 and 2007–2009).

, 2013
Lines are quadratic fits to the mean group size data illustrating: (a) density-dependent change in females, including negative density-dependence at low density; and (b) weak density dependence for males.
Ryan K. Brook (104851), Eric Vander Wal (104846), Floris M. van Beest (104847)   +2 more
core   +1 more source

Misreading or living in denial? Reindeer overstocking and long‐term effects on vegetation: An experimental approach

Ecosphere
In an era marked by accelerating climate change, habitat loss, and shifting land use patterns, it is crucial to understand the intricate effects of multiple stressors on ecosystems.
Bård‐Jørgen Bårdsen, Hans Tømmervik, Marius Warg Næss, Jarle Werner Bjerke   +3 more
doaj   +1 more source