Results 91 to 100 of about 4,049,770 (316)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Freeze or flee? : negative stimuli elicit selective responding
Humans preferentially attend to negative stimuli. A consequence of this automatic vigilance for negative valence is that negative words elicit slower responses than neutral or positive words on a host of cognitive tasks.
Estes, Zachary, Verges, Michelle
core +1 more source
BJPsych Open, 2018 BackgroundPsychotherapy can alleviate mental distress and improve quality of life, but little is known about its potential negative effects and how to determine their frequency.AimsTo present a commentary on the current understanding and future research ...
Alexander Rozental +6 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The biomechanics of negative-pressure wound therapy
, 2011 Includes references.Despite the success of negative-pressure wound therapy, its mechanism of action remains unclear. The common perception that it reduces tissue pressure and increases perfusion has recently been challenged following the observation that
Kairinos, Nicolas
core
HeritageGeoheritage is commonly regarded as an important natural resource for tourism, but the latter can be a factor of risk to the former. A case study in the Western Caucasus, where the rural area of Mountainous Adygeya hosts many geosites (including those ...
Anna V. Mikhailenko, Dmitry A. Ruban
doaj +1 more source
THE FAILURE OF THE JIU VALLEY, THE CONSEQUENCE OF SOME WRONG GOVERNMENT DECISIONS [PDF]
Annals of the University of Petrosani: Economics, 2014 This research is part of a series of field sociologic surveys realized by us over many years and have decided to find out, successively as many elements, related to the specific of the Jiu Valley.
IOAN VALENTIN FULGER, ION HIRGHIDUŞI
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Yixue yu zhexueWith the deep integration of modern technology and clinical medicine, the field of obstetrics and gynecology has established a comprehensive technical framework ranging from surgical interventions to molecular mechanism research.
Shiti ZHANG, Haiying ZHANG
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source