Results 41 to 50 of about 226,864 (256)

Industrial Carbon Emission Efficiency of Cities in the Pearl River Basin: Spatiotemporal Dynamics and Driving Forces

open access: yesLand, 2022
In the context of green and high-quality development, effectively enhancing industrial carbon emission efficiency is critical for reducing carbon emissions and achieving sustainable economic growth.
Hongtao Jiang   +5 more
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Perspectives of CO2 utilization as a negative emission technology

open access: yesSustainable Energy Technologies and Assessments, 2022
International ...
Desport, Lucas, Selosse, Sandrine
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Biochar as a negative emission technology: A synthesis of field research on greenhouse gas emissions

open access: yesJournal of Environmental Quality, 2023
AbstractBiochar is one of the few nature‐based technologies with potential to help achieve net‐zero emissions agriculture. Such an outcome would involve the mitigation of greenhouse gas (GHG) emission from agroecosystems and optimization of soil organic carbon sequestration.
Raj K. Shrestha   +7 more
openaire   +2 more sources

Olivine and dissolved alkalinity trigger different bacterial community shifts in water and oyster gills: insights from a mesocosm experiment

open access: yesFrontiers in Microbiomes
Ocean Alkalinity Enhancement (OAE) is a proposed marine carbon dioxide removal strategy that increases seawater buffering capacity and CO2 uptake through the addition of alkaline substances.
Dominik Antoni   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Do Information Communication Technology and Economic Development Impact Environmental Degradation? Evidence From the GCC Countries

open access: yesFrontiers in Environmental Science, 2022
The environmental variations compel global countries for restructuring economic growth policies to ensure reliable energy usage. Ecological sustainability is a leading concern of the world for adequate and smooth survival of human beings.
Awwad Saad Awwad Al-shammari   +2 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Econometric analysis of the effects of globalization, technology innovation and renewable energy consumption on CO2 emissions: Evidence from top five CO2 -emitting countries

open access: yesJournal of Air Pollution and Health
Introduction: Anthropogenic CO2 emission is a pressing global challenge wreaking serious health, environmental and socioeconomic havocs which require urgent attention.
Abiodun Samuel Isayomi   +2 more
doaj   +1 more source

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