Results 41 to 50 of about 214,541 (256)

Carbon capture and storage (CCS): development path based on carbon neutrality and economic policy

Carbon Neutrality, 2022
In order to limit global warming to 2 °C, countries have adopted carbon capture and storage (CCS) technologies to reduce greenhouse gas emission. However, it is currently facing challenges such as controversial investment costs, unclear policies, and ...
Minghai Shen, Fulin Kong, Lige Tong, Yang Luo, Shaowu Yin, Chuanping Liu, Peikun Zhang, Li Wang, Paul K. Chu, Yulong Ding   +9 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Industrial Carbon Emission Efficiency of Cities in the Pearl River Basin: Spatiotemporal Dynamics and Driving Forces

Land, 2022
In the context of green and high-quality development, effectively enhancing industrial carbon emission efficiency is critical for reducing carbon emissions and achieving sustainable economic growth.
Hongtao Jiang, Jian Yin, Yuanhong Qiu, Bin Zhang, Yi Ding, Ruici Xia   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The effect of ocean alkalinity enhancement on pelagic bacterial communities: focus points derived from a mesocosm experiment

Frontiers in Microbiomes
Anthropogenic climate change caused by CO2 emissions forces humanity to reduce the usage of fossil fuels. Along with the task of emission reduction, societies face the task of removing excess CO2 from the atmosphere by using negative emission ...
Dominik Antoni, Antje Wichels, Maarten Boersma, Maarten Boersma, Maarten Boersma, Gunnar Gerdts   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Biochar as a negative emission technology: A synthesis of field research on greenhouse gas emissions

Journal of Environmental Quality, 2023
AbstractBiochar is one of the few nature‐based technologies with potential to help achieve net‐zero emissions agriculture. Such an outcome would involve the mitigation of greenhouse gas (GHG) emission from agroecosystems and optimization of soil organic carbon sequestration.
Raj K. Shrestha, Pierre‐Andre Jacinthe, Rattan Lal, Klaus Lorenz, Maninder P. Singh, Scott M. Demyan, Wei Ren, Laura E. Lindsey   +7 more
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Olivine and dissolved alkalinity trigger different bacterial community shifts in water and oyster gills: insights from a mesocosm experiment

Frontiers in Microbiomes
Ocean Alkalinity Enhancement (OAE) is a proposed marine carbon dioxide removal strategy that increases seawater buffering capacity and CO2 uptake through the addition of alkaline substances.
Dominik Antoni, Marco Rump, Gunnar Gerdts   +2 more
doaj   +1 more source

Do Information Communication Technology and Economic Development Impact Environmental Degradation? Evidence From the GCC Countries

Frontiers in Environmental Science, 2022
The environmental variations compel global countries for restructuring economic growth policies to ensure reliable energy usage. Ecological sustainability is a leading concern of the world for adequate and smooth survival of human beings.
Awwad Saad Awwad Al-shammari, Saqib Muneer, Abhishek Tripathi   +2 more
doaj   +1 more source