Results 91 to 100 of about 813,030 (307)

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

Advanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua, Anira Escrichs, Yonatan Sanz Perl, Morten L. Kringelbach, Adele Diamond, Solange Denervaud, Gustavo Deco   +6 more
wiley   +1 more source

Differential emotional processing in concrete and abstract words [PDF]

, 2018
Emotion (positive and negative) words are typically recognized faster than neutral words. Recent research suggests that emotional valence, while often treated as a unitary semantic property, may be differentially represented in concrete and abstract ...
Bruce, Gillian, Keitel, Anne, O'Donnell, Patrick J, Scott, Graham G, Sereno, Sara C, Yao, Bo   +5 more
core   +7 more sources

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Preventing worry and rumination by induced positive emotion

International Journal of Preventive Medicine, 2012
Background: Thus study aimed to test the hypothesis that positive emotion can quell or undo the lingering worry and rumination following induced negative emotion. Methods: 32 female students in grade 1 of high school were randomly recruited and assigned
Fatemeh Bahrami, Rahim Kasaei, Ahmadreza Zamani   +2 more
doaj  

The Problem of Spite

, 2013
Spite is one of the most negative emotions. It ranges from the ruthless, malicious, and enormously destructive, to the trivial and seemingly harmless.
Florey, David M.
core  

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Mechanisms underlying the alleviation of negative emotions from social exclusion by interpersonal emotion regulation

Scientific Reports
Negative emotions induced by social exclusion can exert a significant detrimental effect on an individual’s physical and mental health. To explore the effects and neural mechanisms of interpersonal emotion regulation on the negative emotions caused by ...
Zhi Zhu, Meng Zhou, Manzhi Wang, Jingyao Pu, Yun Tao, Xie Ma   +5 more
doaj   +1 more source

Biosignals as an Advanced Man-Machine Interface [PDF]

, 2009
As is known for centuries, humans exhibit an electrical profile. This profile is altered through various physiological processes, which can be measured through biosignals; e.g., electromyography (EMG) and electrodermal activity (EDA).
Broek, Egon L. van den, Lisy, Viliam, Schut, Marleen H., Tuinenbreijer, Kees, Westerink, Joyce H.D.M.   +4 more
core   +4 more sources

The impact of the Russia–Ukraine war on stock prices, profits and perceptions in the food supply chain

Agribusiness, EarlyView.
Abstract The Russian invasion of Ukraine in February 2022 had profound consequences for the global economy. As both countries are major commodity exporters, the food value chain was also affected. This study investigates the impact of the invasion on stock prices, profitability and sentiments of agribusinesses along the food supply chain by using an ...
Julia Höhler, Ivo Harmens, Alfons Oude Lansink   +2 more
wiley   +1 more source