This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu +4 more
wiley +1 more source
Interoception primes negative emotion processing during cognitive reappraisal: Electroencephalographical evidence. [PDF]
Chen L, Chen F, Bo K, Sun J, Zhou R.
europepmc +1 more source
Objective The objective of this study was to investigate the ability of patient‐reported/administered outcomes to capture disability worsening and progression independent of relapse activity (PIRA) in multiple sclerosis (MS). Methods We included patients from the longitudinal multicenter MS PATHS cohort with ≥3 assessments and >6 months follow‐up. PIRA
Evy M. Reinders +40 more
wiley +1 more source
Negative Emotion Differentiation Promotes Cognitive Reappraisal: Evidence From Electroencephalogram Oscillations and Phase-Amplitude Coupling. [PDF]
Wang Y, Shangguan C, Li S, Zhang W.
europepmc +1 more source
A new Patient‐Reported Outcome Scale to assess autoimmune Encephalitis: PROSE
Objective Autoimmune encephalitis (AIE) has long‐lasting effects. Generic clinical assessment‐scales insufficiently capture disease‐specific sequelae. Patient‐reported outcome measures (PROMs) assess outcomes important to patients, ensuring relevance in the clinic and trials.
Juliette Brenner +24 more
wiley +1 more source
Doctors' Abusive Supervision and Patients' Deviant Behavior in Taizhou, China: The Mediating Role of Patients' Negative Emotion. [PDF]
Luo C, Tung TH, Chen HX.
europepmc +1 more source
Objective Disease activity plays a central role in rheumatoid arthritis (RA) clinical studies. The inconsistent availability of data on disease activity in real‐world electronic health records (EHRs) data has limited the ability to generate real‐world evidence (RWE).
David Cheng +34 more
wiley +1 more source
More empathy for others, more hurt for oneself? Empathy for pain is related to poor mental health and negative emotion regulation. [PDF]
Li M +7 more
europepmc +1 more source
Moving beyond neurophobia to cultivate the neuroquisitive learner
Abstract “Neurophobia,” a pervasive fear of the neurological sciences, poses a significant barrier in medical education, affecting learners and physicians worldwide. Its consequences are far‐reaching, contributing to a limited neurology workforce and diminished confidence among non‐specialists in managing neurological conditions.
Joanna R. Appel +1 more
wiley +1 more source
Predicting the strength of next-day negative emotion states in body dysmorphic disorder using passive smartphone data: An intensive longitudinal assessment study. [PDF]
Weingarden H +6 more
europepmc +1 more source

