Results 151 to 160 of about 880,785 (306)

The role of AI face-swapping technology anxiety in negative eWOM contagion: SEM and fsQCA findings

Humanities & Social Sciences Communications
Negative electronic word of mouth (eWOM) is a critical barrier to the diffusion of new technologies. Understanding the mechanisms underlying negative eWOM contagion can assist new technology providers in mitigating the effects of such contagion.
Xing-Zheng Xie, Qiu-Ting Duan
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Nineteenth-century English politeness: Negative politeness, conventional indirect requests and the rise of the individual self

, 2011
In this paper we argue that the kind of individualistic ethos Brown and Levinson's (1987) politeness model is accused of — and in particular its notion of (non-imposition) negative face — is not simply a reflection of British culture, but a reflection of
Jonathan Culpeper, Jane Demmen, Demmen, Jane, Culpeper, Jonathan   +3 more
core   +1 more source

Study on air leakage law and gas extraction effect of “high drainage roadway + Y-type ventilation” working face

Meikuang Anquan
In recent years, the gas control method of “Y-type ventilation+ high drainage roadway” has been widely used with its superior control effect. Affected by the negative pressure of high extraction roadway, the air leakage law of working face is more ...
Huhu LI, Yucheng LI, Xuelin YANG, Huan ZHANG, Kunzhao LI, Yanan WU   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The impact of awareness on affective emoji priming in visual word recognition

Scientific Reports
Emojis have become integral to digital communication, yet their impact on downstream cognitive processing is not fully understood. In two lexical decision experiments, we examined the behavioral and electrophysiological effects of emoji primes that ...
Demian Stoianov, Elisabeth Beyersmann, Nenagh Kemp, Signy Wegener, Srdjan Popov   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Black Face Minstrels (1904)

, 1904
This glass negative shows Springfield College alumni Frederick A. Henckel (left, class of 1904) and Roy F. Seymour (right, class of 1904) posing as black face minstrels. The sheet music shown is "I Hates to Get Up Early in de Morn,” which was written by

core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source