Results 41 to 50 of about 422,709 (217)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Combating the 'Sick Building Syndrome' by Improving Indoor Air Quality

Australasian Journal of Construction Economics and Building, 2012
Research indicates that many of symptoms attributed to the Sick Building Syndrome in air-conditioned office buildings are a result of considerably reduced negative ions in the internal atmosphere and that replacing the depleted negative ions can improve ...
Pongchai Nimcharoenwon, Graham Miller
doaj   +3 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Sterilization Effect and Mechanism of Negative Ions in Refrigerator [PDF]

Shipin Kexue
In this study, Staphylococcus, Candida and Penicillium that had been isolated and purified from commercial salmon, chicken breast and citrus in our laboratory were used as target microorganisms to explore the sterilization effect and mechanism of ...
HU Haimei, JIANG Feng, CHEN Kaisong, LIU Gangshuai, JIA Wen, FU Daqi
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Transport of F- ions in gaseous environment for technological applications [PDF]

FME Transactions, 2013
In this work we present swarm data obtained for F- ions in atomic and molecular gases necessary to form the global models for the complex collisional plasmas.
Jovanović Jasmina V., Raspopović Zoran M., Stojanović Vladimir D., Nikitović Željka D.   +3 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Piezoelectric air ionizer with smooth performance control

Технологія та конструювання в електронній апаратурі, 2006
The problem of creating piezoelectric air ionizers with smooth performance control is considered. A method of smooth regulation of negative ion output is proposed, which is based on discretization of the ionization process.
Yu. E. Paerand, O. I. Zakhozhay
doaj  

Numerical Simulation of the Dynamics of RF Capacitive Discharge in Carbon Dioxide

East European Journal of Physics
In this research, the one-dimensional fluid code SIGLO-rf was used to study the internal parameters of RF capacitive discharge in carbon dioxide, focusing mainly on time-averaged and spatio-temporal distributions of discharge parameters. With the help of
Valeriy Lisovskiy, Stanislav Dudin, Amaliya Shakhnazarian, Pavlo Platonov, Vladimir Yegorenkov   +4 more
doaj   +1 more source