Results 61 to 70 of about 57,391 (278)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Additive presuppositions are derived through activating focus alternatives [PDF]

open access: yes, 2017
The additive presupposition of particles like "too"/"even" is uncontested, but usually stipulated. This paper proposes to derive it based on two properties. (i) "too"/"even" is cross-linguistically focus-sensitive, and (ii) in many languages, "too"/"even"
Szabolcsi, Anna
core  

Affect Analysis of Radical Contents on Web Forums Using SentiWordNet [PDF]

open access: yes, 2013
The internet has become a major tool for communication, training, fundraising, media operations, and recruitment, and these processes often use web forums.
Chalothorn, Tawunrat, Ellman, Jeremy
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Made and Metalinguistic Negation in Japanese() [PDF]

open access: yes, 2004
1. Introduction This paper addresses Japanese metalinguistic negation and Negative Polarity Items (henceforth NPIs). In the course of discussion, we clarify a different morphology between descriptive use of negation and metalinguistic one. ..
Yoshida Takashi
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Ouk ´Ismen Oudén: Negative Concord and Negative Polarity in the History of Greek [PDF]

open access: yes, 2013
In Ancient Greek a single set of indefinite enclitic pronouns was used indifferently in both negative/affective environments (i.e. like negative polarity items (NPI)) and in positive ones (i.e. like positive polarity items (PPI)).
Horrocks, Geoffrey
core   +1 more source

Crowdsourcing a Word-Emotion Association Lexicon [PDF]

open access: yes, 2012
Even though considerable attention has been given to the polarity of words (positive and negative) and the creation of large polarity lexicons, research in emotion analysis has had to rely on limited and small emotion lexicons.
Mohammad, Saif M., Turney, Peter D.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Preverbs, Postpositions and Indefinite Pronouns in Hittite

open access: yesAtti del Sodalizio Glottologico Milanese, 2017
The paper deals with the syntax of preverbs, postpositions (including postpositional phrases) and existential quantifiers/ negative polarity items in Hittite within the Minimalist Program. Their in-situ and ex-situ positions are determined.
Andrej Sideltsev
doaj   +1 more source

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