Results 61 to 70 of about 144,272 (327)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

An efficient Map Reduce-Based Hybrid NBC-TFIDF algorithm to mine the public sentiment on diabetes mellitus – A big data approach

open access: yesJournal of King Saud University: Computer and Information Sciences, 2021
The increase in the usage of internet and social media has enabled people exchange views, opinions and thoughts as never before. This exchange of data has paved the way for sentiment analysis.
J. Ramsingh, V. Bhuvaneswari
doaj   +1 more source

A critical assessment of exhaustivity for Negative Polarity Items

open access: yesActa Linguistica Academica, 2018
In some recent works on negative polarity, exhaustivity is posited as the single defining property of all negative polarity item (NPI) and free choice item (FCI) paradigms.
A. Giannakidou
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Processing Sentences With Multiple Negations: Grammatical Structures That Are Perceived as Unacceptable

open access: yesFrontiers in Psychology, 2019
This investigation draws from research on negative polarity item (NPI) illusions in order to explore a new and interesting instance of misalignment observed for grammatical sentences containing two negative markers.
Iria de-Dios-Flores, Iria de-Dios-Flores
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Fragment answers and double negation in strict negative concord languages [PDF]

open access: yes, 2016
International audienceThis paper revisits the phenomenon of negative concord (NC) as an instance of polarity sensitivity. We shed light on a new set of data regarding n-words as fragment answers to negative questions and show that we find unexpected ...
Falaus, Anamaria, Nicolae, Andreea
core   +5 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Distributionally constrained items in child language: the acquisition of superweak NPI shenme ‘a/some’ in Mandarin Chinese

open access: yesGlossa, 2017
This paper presents new experimental results obtained from 88 Mandarin speaking children (2; 11 – 4; 09; M = 3; 11; SD = 0; 6; 44 girls) in their acquisition of shenme ‘a/some’, a prototypical superweak Negative Polarity Item (NPI) that survives in ...
Jing Lin
doaj   +2 more sources

Evolution of magnetic fields and energetics of flares in active region 8210 [PDF]

open access: yes, 2006
To better understand eruptive events in the solar corona, we combine sequences of multi-wavelength observations and modelling of the coronal magnetic field of NOAA AR 8210, a highly flare-productive active region.
Andersen, Rune K.   +3 more
core   +2 more sources

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