Results 151 to 160 of about 3,708,738 (393)

Predictive validity of the HCR-20 for violent and non-violent sexual behaviour in a secure mental health service [PDF]

, 2015
BackgroundViolent and non-violent sexual behaviour is a fairly common problem among secure mental health service patients, but specialist sexual violence risk assessment is time-consuming and so performed infrequently.AimsWe aimed to establish whether a ...
Dickens, Geoffrey L., Knight, Caroline, Mason, Fiona L., O'Shea, Laura E., Picchioni, Marco M., Thaker, Dev-Kishan   +5 more
core   +2 more sources

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Validation of colorectal cancer surgery data from administrative data sources

BMC Medical Research Methodology, 2012
Background Surgery is the primary treatment for colorectal cancer for both curative and palliative intent. Availability of high quality surgery data is essential for assessing many aspects of the quality of colorectal cancer care.
Li Xue, King Charlotte, deGara Christopher, White Jonathon, Winget Marcy   +4 more
doaj   +1 more source

Uji Diagnostik Penentuan Jenis Kelamin Metode Pemeriksaan Drumstick Neutrofil Dibandingkan dengan Metode Pemeriksaan Amelogenin Dna (Deoxyribonucleic Acid) [PDF]

, 2013
The procedural and cost need for drumstick neutrophyl test as we know is more simple and cheap just than amelogenin DNA test. A few researches show the function of drumstick neutrophyl test and amelogenin DNA test forgender determination especially for ...
Nirmalasari, N. (Nila), Nurhantari, Y. (Yudha), Riyanto, B. U. (Bambang)   +2 more
core  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Interpretation of a diagnostic test in statistical terms

Current Medicine Research and Practice, 2012
In medical practice, various tests are used for confirmation or diagnosis of a disease. For clinical implications, these tests are compared with the definitive test which is the gold standard and their diagnostic utility is expressed by various ...
Vivek Choudhury, Anita Singh, Satish Saluja   +2 more
doaj  

Magnetic resonance mammography in the evaluation of recurrence at the prior lumpectomy site after conservative surgery and radiotherapy [PDF]

, 2006
INTRODUCTION: The aim was to assess the value of magnetic resonance mammography (MRM) in the detection of recurrent breast cancer on the prior lumpectomy site in patients with previous conservative surgery and radiotherapy.
A Rieber, AD Murray, American College of Radiology, B Fisher, C Boetes, C Schorn, CE Soderstrom, CK Kuhl, Daniela Origgi, DD Dershaw, Enrico Cassano, Gaetano Villa, H Mumtaz, I Isomoto, JP Stack, K Kinkel, L Liberman, Lorenzo Preda, Luca Bazzi, LW Nunes, M Kawashima, M Tozaki, Massimo Bellomi, N Morakkabati, P Belli, P Viehweg, PL Davis, R Gilles, RD Muuller, RW Kerslake, S Kramer, SG Orel, SH Heywang, SH Heywang, SH Heywang-Kobrunner, Stefania Rizzo, TH Dao, U Fischer, U Veronesi, VT De Vita, WA Kaiser   +40 more
core   +2 more sources

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study. [PDF]

, 2011
To validate the clinical efficacy and practical feasibility of massively parallel maternal plasma DNA sequencing to screen for fetal trisomy 21 among high risk pregnancies clinically indicated for amniocentesis or chorionic villus sampling.
Akolekar, R, Au-Yeung, SKC, Chan, KCA, Chiu, RWK, Go, ATJI, Kung, YY, Lam, H, Lau, ET, Lau, TK, Leung, TY, Leung, WC, Lo, YMD, Lun, FMF, Minekawa, R, Nicolaides, KH, Oudejans, CBM, Sun, H, Tang, MHY, Tang, RYK, To, WWK, Van Vugt, JMG, Wang, J, Zhang, X, Zheng, YWL   +23 more
core   +3 more sources

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source