Results 61 to 70 of about 1,591,983 (307)

Comparison of the bedside head impulse test with the video head impulse test in a clinical practice setting: a prospective study of 500 outpatients.

Frontiers in Neurology, 2016
Objectives: The primary aim was to determine the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the bedside head impulse test (bHIT) using the video HIT (vHIT) as the gold standard for quantifying the ...
Chun Wai eYip, Chun Wai eYip, Miriam eGlaser, Claudia eFrenzel, Otmar eBayer, Michael eStrupp   +5 more
doaj   +1 more source

Role of HRCT for Rapid Triage of Patients with COVID-19 Pneumonia

Journal of Rawalpindi Medical College, 2021
Background:   To assess the diagnostic performances of HRCT for COVID 19 pneumonia for efficient triage of patients, in comparison with RT-PCR reverse transcription polymerase chain reaction test.
Hina Hafeez Abbasi, Misbah Durrani, Umme Kalsoom, Anum Zahoor, Fizza Batool, Shawana Sharif   +5 more
doaj   +1 more source

Sensitivity and Specificity of Rapid Diagnostic Test with Microscopic Gold Standard to Identify Plasmodium Species [PDF]

, 2016
Malaria is a main health problem in islands area which is under developed and isolated. Nation-wide, in 2014 Maluku province was recorded to have Annual Malaria Incident (AMI) value of 30.4%, positive incidents of 13.30%, ABER 3.76%, SPR 21.50%, and ...
Arwati, H. (Heny), Dachlan, Y. P. (Yoes), Keman, S. (Sudjajadi), Sillehu, S. (Sahrir)   +3 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Sequential battery of COVID-19 testing to maximize negative predictive value before surgeries

Revista do Colégio Brasileiro de Cirurgiões, 2020
SARS-CoV-2 is a novel virus which has proven to be highly contagious. Specific viral dynamics and immune response to the virus are yet to be fully defined and determining the sensitivity and specificity of the available testing methods is still a work in
NEERAJ SINHA, GALIT BALAYLA
doaj   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Validating teachers for Visual Acuity Screening in rural South African schools

African Vision and Eye Health
Background: Early detection of a reduction in visual acuity (VA) in children is crucial for their education, job prospects, and overall well-being. In many regions, this is deficient because of limited access to eye-care services, adversely affecting the
Pirindhavellie Govender-Poonsamy, Khathutshelo P. Mashige, Ashtaleena Bhawanibik, Nokwanda A. Maphanga, Nomfundo Mngadi, Silubone Neno, Nosipho T. Ngcobo, Niniza F. Sangweni, Ving F. Chan   +8 more
doaj   +1 more source

Asymptotic properties of the sequential empirical ROC, PPV and NPV curves under case-control sampling

, 2012
The receiver operating characteristic (ROC) curve, the positive predictive value (PPV) curve and the negative predictive value (NPV) curve are three measures of performance for a continuous diagnostic biomarker.
Feng, Ziding, Koopmeiners, Joseph S.
core   +1 more source

Motility Indole Urease as an Alternative Diagnostic Method for Identifying Helicobacter Pylori Infection [PDF]

, 2001
Background: The prevalence of Helicobacter pylori (H. pylori) infection in the world is quite high, especially in developing countries. Usually the patient shows no specific symptoms and chronic gastritis therefore becomes chronically infected.
Kumala, W. (Widyasari), Rani, A. A. (Abdul)   +1 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source