Results 81 to 90 of about 743,467 (306)

Tuberculosis and air travel: Systematic review and analysis of policy

, 2010
WHO international guidelines for the control of tuberculosis in relation to air travel require—after a risk assessment—tracing of passengers who sat for longer than 8 h in rows adjacent to people with pulmonary tuberculosis who are smear positive or ...
Abubakar, Ibrahim
core   +1 more source

Utility of dipstick urinalysis in the diagnosis of urinary tract infections among outpatients in Mwanza and Dar es Salaam regions in Tanzania

Bulletin of the National Research Centre
Background Globally, urinary tract infections (UTIs) are the leading cause of hospital visits, especially among women. In many developing countries, especially in lower health facilities, the dipstick urinalysis is the most commonly requested test, as ...
Salim S. Masoud, Mtebe Majigo, Vitus Silago, Peter Kunambi, Helmut Nyawale, Nyambura Moremi, Erick Komba, Fauster X. Mgaya, Emmanuel Magembe, Mariam M. Mirambo, Stephen E. Mshana, Mecky Isaac Matee   +11 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Intussusception; deriving true prevalence, specificity and negative predictive value from the observed prevalence, sensitivity and positive predictive value.

, 2020
Intussusception; deriving true prevalence, specificity and negative predictive value from the observed prevalence, sensitivity and positive predictive value.
Rosa Gini (451348), Tom De Smedt (5400662), Kaatje Bollaerts (2266669), Caitlin Dodd (324051), Nick Andrews (151232), Alexandros Rekkas (8748450)   +5 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Validation of Postsurgical Venous Thromboembolism Diagnoses of Patients Undergoing Lower Limb Orthopedic Surgery in the Danish National Patient Registry

Clinical Epidemiology, 2022
Josephine Galsklint,1 Søren Kold,2,3 Søren Risom Kristensen,1,2 Marianne Tang Severinsen,2,4 Inger Lise Gade2,4,5 1Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark; 2Department of Clinical Medicine, Aalborg University ...
Galsklint J, Kold S, Kristensen SR, Severinsen MT, Gade IL   +4 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Sensitivity, specificity, negative predictive value, and positive predictive value of S ser. Typhi IgM/IgG rapid test.

, 2014
TP, true positive; FN, false negative; FP, false positive; FN, false negative.Sensitivity, specificity, negative predictive value, and positive predictive value of S ser. Typhi IgM/IgG rapid test.
Narong Henpraserttae (655628), Wannee Limpitikul (580302), Kamolwish Laoprasopwattana (424106), Rachanee Saksawad (655629)   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparison of sensitivity, specificity, positive predictive value, and negative predictive value across different rater comparisons.

Comparison of sensitivity, specificity, positive predictive value, and negative predictive value across different rater comparisons.
Stefan Birkett (14526272), Simon Nichols (6836987), James Metcalfe (17286826), Stuart Ennis (5504579), Richard Powell (290871), Brian Begg (14526273), Prithwish Banerjee (583124), Thomas Nickolay (18121412), Gordon McGregor (5504588), Lee Ingle (21150), Angela Hoye (6988172), Rob Shave (11913643)   +11 more
core   +1 more source