Results 81 to 90 of about 10,382,769 (301)

Validating teachers for Visual Acuity Screening in rural South African schools

African Vision and Eye Health
Background: Early detection of a reduction in visual acuity (VA) in children is crucial for their education, job prospects, and overall well-being. In many regions, this is deficient because of limited access to eye-care services, adversely affecting the
Pirindhavellie Govender-Poonsamy, Khathutshelo P. Mashige, Ashtaleena Bhawanibik, Nokwanda A. Maphanga, Nomfundo Mngadi, Silubone Neno, Nosipho T. Ngcobo, Niniza F. Sangweni, Ving F. Chan   +8 more
doaj   +1 more source

The new accounting for expected adjusted effect test (AEAE test) has higher positive predictive value than a zero-order significance test

BMC Research Notes, 2021
Objective The present simulation study aimed to assess positive predictive value (PPV) and negative predictive value (NPV) for our newly introduced Accounting for Expected Adjusted Effect test (AEAE test) and compare it to PPV and NPV for a traditional ...
Kimmo Sorjonen, Gustav Nilsonne, Bo Melin, Michael Ingre   +3 more
doaj   +1 more source

Intussusception; deriving true prevalence, specificity and negative predictive value from the observed prevalence, sensitivity and positive predictive value.

, 2020
Intussusception; deriving true prevalence, specificity and negative predictive value from the observed prevalence, sensitivity and positive predictive value.
Rosa Gini (451348), Tom De Smedt (5400662), Kaatje Bollaerts (2266669), Caitlin Dodd (324051), Nick Andrews (151232), Alexandros Rekkas (8748450)   +5 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Tuberculosis and air travel: Systematic review and analysis of policy

, 2010
WHO international guidelines for the control of tuberculosis in relation to air travel require—after a risk assessment—tracing of passengers who sat for longer than 8 h in rows adjacent to people with pulmonary tuberculosis who are smear positive or ...
Abubakar, Ibrahim
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Utility of dipstick urinalysis in the diagnosis of urinary tract infections among outpatients in Mwanza and Dar es Salaam regions in Tanzania

Bulletin of the National Research Centre
Background Globally, urinary tract infections (UTIs) are the leading cause of hospital visits, especially among women. In many developing countries, especially in lower health facilities, the dipstick urinalysis is the most commonly requested test, as ...
Salim S. Masoud, Mtebe Majigo, Vitus Silago, Peter Kunambi, Helmut Nyawale, Nyambura Moremi, Erick Komba, Fauster X. Mgaya, Emmanuel Magembe, Mariam M. Mirambo, Stephen E. Mshana, Mecky Isaac Matee   +11 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Sequential battery of COVID-19 testing to maximize negative predictive value before surgeries

Revista do Colégio Brasileiro de Cirurgiões, 2020
SARS-CoV-2 is a novel virus which has proven to be highly contagious. Specific viral dynamics and immune response to the virus are yet to be fully defined and determining the sensitivity and specificity of the available testing methods is still a work in
NEERAJ SINHA, GALIT BALAYLA
doaj   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source