Results 61 to 70 of about 10,382,769 (301)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk   +10 more
wiley   +1 more source

A comparative analysis of the different HIV testing techniques used in Zambia: data from a clinical performance study

open access: yesBMC Research Notes
Background Approximately 40 million people globally are living with HIV (PLWH) and more than 50% of these PLWH reside in Eastern and Southern Africa. Zambia has an adult HIV-1 prevalence (ages 15–49) of 11.1 [10.5–11.6] %, among the highest in the world (
Loveness Mukuka   +4 more
doaj   +1 more source

Bayesian Youden index for algorithmic evaluation under class imbalance: mathematical foundations with applications to insulin resistance and diabetes progression

open access: yesFrontiers in Epidemiology
BackgroundThe evaluation of binary classifiers under real-world conditions requires metrics that account for the dependence of predictive performance on disease prevalence.
Aquiles Darghan   +5 more
doaj   +1 more source

Sensitivity, specificity, Positive Predictive Value (PPV), and Negative Predictive Value (NPV) of PWD thresholds for DepMap essential gene identification.

open access: yes, 2021
Sensitivity, specificity, Positive Predictive Value (PPV), and Negative Predictive Value (NPV) of PWD thresholds for DepMap essential gene identification.
Paul Marjoram (28920)   +3 more
core   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad   +9 more
wiley   +1 more source

The predictive value of a QuantiFERON conversion in the development of active tuberculosis disease in adolescents [PDF]

open access: yes, 2011
This study is an extension of a prospective epidemiological study of TB disease and infection in adolescents in the Worcester and surrounding areas in the Western Cape carried out from 2005 to 2009, in which 6363 participants were enrolled from local ...
Machingaidze, Shingai
core   +1 more source

The importance of a patient’s background in formulating a management approach

open access: yesHealthcare in Low-resource Settings, 2013
Peptic ulcer disease is uncommon in childhood, with non-specific clinical features. A tendency to late diagnosis makes it more likely for a patient to present with complications.
Anil Ojha   +2 more
doaj   +1 more source

Sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic odds ratio of algorithm set E.

open access: yes, 2019
Sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic odds ratio of algorithm set E.
Norin Kameyama (7224944)   +7 more
core   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Information Graphs Incorporating Predictive Values of Disease Forecasts

open access: yesEntropy, 2020
Diagrammatic formats are useful for summarizing the processes of evaluation and comparison of forecasts in plant pathology and other disciplines where decisions about interventions for the purpose of disease management are often based on a proxy risk ...
Gareth Hughes   +2 more
doaj   +1 more source

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