Results 101 to 110 of about 10,382,769 (301)

Sensitivity, specificity, positive predictive value and negative predictive value of ApneaLink^TM autoscore compared with polysomnography.

, 2018
Sensitivity, specificity, positive predictive value and negative predictive value of ApneaLinkTM autoscore compared with polysomnography.
Sabrina Maier (5318102), Jörg Daniel Leuppi (2635099), Michel Hug (5318105), Stig Solbach (5318108), Stefanie Brighenti-Zogg (2635087), David Miedinger (330274), Katrin Uehli (5318099), Selina Dürr (5318111)   +7 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio of different cut-off values of PCT on SeptiFast results.

, 2013
PPV = positive predictive value.NPV = negative predictive value.LR+ = positive likelihood ratio.LR− = negative likelihood ratio.
Christian Leli (292048), Amedeo Moretti (292051), Angela Cardaccia (292049), Rita Pagliochini (292057), Francesco D'Alò (292053), Antonella Mencacci (292047), Mariella Barcaccia (292058), Francesco Bistoni (184196), Marta Meucci (292050), Senia Farinelli (292055)   +9 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Sensitivity, specificity, positive predictive value and negative predictive value of S₈ and S₂₄.

, 2018
Sensitivity, specificity, positive predictive value and negative predictive value of S8 and S24.
Paul Meyvisch (5537300), Koen Andries (346051), Chrispin Kambili (707561), Nacer Lounis (355090), Ariel Alonso (709471), Myriam Theeuwes (5537297), Brian Dannemann (5537303), Geert Molenberghs (43335), Wim Van der Elst (3824152), An Vandebosch (3741457)   +9 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The value of the negative predictive values [PDF]

BJOG: An International Journal of Obstetrics & Gynaecology, 1999
openaire   +2 more sources

Quantification of Metamorphopsia in Resolved Idiopathic Central Serous Chorioretinopathy: An Analysis Using M-CHARTS, Amsler Grid, and Optical Coherence Tomography

Clinical Ophthalmology
Barsha Suwal,1 Deepak Khadka,1 Arjun Shrestha,1 Rinkal Suwal,2 Bijay Khatri3 1Department of Ophthalmology, BP Eye Foundation, Hospital for Children, Eye, ENT, and Rehabilitation Services, Bhaktapur, Nepal; 2Department of Optometry, BP Eye Foundation ...
Suwal B, Khadka D, Shrestha A, Suwal R, Khatri B   +4 more
doaj  

Interpretation of a diagnostic test in statistical terms

Current Medicine Research and Practice, 2012
In medical practice, various tests are used for confirmation or diagnosis of a disease. For clinical implications, these tests are compared with the definitive test which is the gold standard and their diagnostic utility is expressed by various ...
Vivek Choudhury, Anita Singh, Satish Saluja   +2 more
doaj