Results 91 to 100 of about 66,443 (291)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

The Importance of Hydration in Wound Healing: Reinvigorating the clinical perspective

, 2016
Balancing skin hydration levels is important as any disruption in skin integrity will result in disturbance of the dermal water balance. The discovery that a moist wound healing environment actively supports the healing response when compared to a dry ...
Cutting, K. F., Ousey, K., Rogers, A. A., Cutting, Keith, Rippon, Mark, Rippon, Mark G., Rogers, Alan A., Ousey, Karen   +7 more
core   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Negative pressure wound therapy with intermittent instillation of rifampin for the treatment of an infected vascular bypass graft

Journal of Vascular Surgery Cases and Innovative Techniques, 2019
Negative pressure wound therapy with intermittent instillation, especially with the addition of antibiotics in the case of infection, is a versatile treatment modality for the closure of wounds and can be used both primarily after débridement and ...
Chrisovalantis Lakhiani, MD, Christopher M. Fleury, MD, Cara K. Black, BA, David E. Janhofer, BS, Cameron Akbari, MD, Karen Kim Evans, MD   +5 more
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Wound moisture tracking in the presence of antibacterial honey and during topical negative pressure therapy

, 2013
Unnecessary dressing changes during military operations in the hospital or at home compromise healing and may increase the risk of local infection. In this article, we describe a medical device that allows the control of moisture in the wound without ...
Connolly, Patricia
core  

Improvement of Therapy Outcomes after Negative Pressure Wound Therapy in a Patient with Acne inversa.

, 2014
Treatment of acne inversa (also known as hidradenitis suppurativa) is complicated and chronic. This debilitating, inflammatory disease of the follicular sacks affects mostly young adults and has a strong negative impact on their quality of life.
Francuzik, Wojciech, Banasiewicz, Tomasz, Adamski, Zygmunt   +2 more
core   +1 more source

The use of a gentamicin-collagen sponge (Garamycin sponge) with NPWT for the treatment of difficult wounds in patients with Chron's disease. A case series

, 2023
Negative pressure wound therapy (NPWT) is extremely important in the treatment of difficult wounds in patients with proctological diseases, including patients with Crohn's colitis.
Banasiewicz, Tomasz, Bartosz Jan Grzechulski   +1 more
core   +1 more source

Early Recognition of Treatment‐Responsive Rapidly Progressive Dementia: The Modified STAM3mP Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Early identification of patients with treatment‐responsive rapidly progressive dementia (RPD) is important as early treatment improves outcomes. The STAM3P score identifies treatment‐responsive RPD using “high risk” presenting features. We optimized performance by adding a time component (i.e., dementia within 3 months) and validated the ...
R. W. van Steenhoven, N. Satyadev, A. E. M. Bastiaansen, Y. D. Piura, J. Kerstens, Y. S. Crijnen, J. Brenner, T. Brand, T. M. Bienfait, S. Veenbergen, J. M. de Vries, F. J. de Jong, E. G. P. Dopper, P. A. E. Sillevis Smitt, H. Seelaar, G. S. Day, M. J. Titulaer   +16 more
wiley   +1 more source

Endoluminal negative pressure wound treatment of anastomotic leakage in rectal surgery patients – critical review of the literature.

, 2015
During past 20 years the use of negative pressure wound therapy (NPWT) has shown it effectivity and efficiency in treatment of different indications.
Daniela Karasová, Huľo, Edward
core   +1 more source