Metagenomic next-generation sequencing contributes to the diagnosis of <i>Gardnerella vaginalis</i> bacteremia associated with a rare extragenital infection and diagnostic challenges in a 13-year-old female patient: A case report. [PDF]
Li X +9 more
europepmc +1 more source
Negative Sequence Current as a Breaker Failure Protection for Medium Voltage Grids
openaire +1 more source
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
A Novel Directional Element for AC Lines in Systems with Inverter-Based Resources. [PDF]
Qian K, Wen M, Xue X, Sun Z.
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Squidly harnesses enzyme functional hierarchy and contrastive learning to efficiently predict catalytic residues from sequence. [PDF]
Rieger WJF, Bodén M, Arnold F, Mora A.
europepmc +1 more source
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
A Novel Unsupervised Learning Model with Bayesian Hyperparameter Optimization for Predicting Substrates of Promiscuous Enzymes. [PDF]
Gao R +6 more
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source

