Results 41 to 50 of about 1,737,272 (214)
BioengineeringThis study aims to develop and validate a multisequence MRI-based radiomics approach for distinguishing metaplastic breast cancer (MBC) from non-metaplastic triple-negative breast cancer (TNBC) at the initial diagnosis, which could facilitate optimal ...
Rana Gunoz Comert +10 more
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Niederländisch toch und Deutsch doch: Gleich oder doch nicht ganz?
Linguistik Online, 2003 In this paper, a semantic analysis is presented of the Dutch particle toch and its German cognate doch. On the formal level they may appear as either adverb, conjunction or interjection, and they also occur in different sentence types.
Ad Foolen
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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BMC Microbiology, 2023 Background In the absence of effective antiviral drugs or vaccines, early and accurate detection of SARS-CoV-2 infection is essential to the COVID-19 pandemic.
Sayyad Khanizadeh +4 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Bio-Protocol, 2017 This protocol provides an easy and rapid method to prepare lipopolysaccharide from the gastric pathogen Helicobacter pylori for visualization on acrylamide gels by silver staining and for detecting the presence of Lewis antigens by Western blot.
Hong Li, Mohammed Benghezal
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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The Role of Emotion Dysregulation, Repetitive Negative Thoughts and Thought-Action Fusion, in Prediction of Worry [PDF]
روانشناسی و روانپزشکی شناخت, 2017 Introduction: Worry is a prevalent phenomenon and common feature in many psychological disorders, especially anxiety disorders. Objective: The aim of this study was to investigate the role of thought-action fusion, emotion dysregulation and repetitive
Goudarzi Z, Akbari M
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