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Primary and Secondary Negative Symptoms in Schizophrenia
Frontiers in Psychiatry, 2022 The negative symptoms of schizophrenia include volitional (motivational) impairment manifesting as avolition, anhedonia, social withdrawal, and emotional disorders such as alogia and affective flattening.
Sergey N. Mosolov +2 more
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Effectiveness of spironolactone on schizophrenia symptoms: A double-blind randomized clinical trial [PDF]
روانشناسی و روانپزشکی شناخت, 2023 Introduction: Schizophrenia is a mental disorder in which the facts surrounding a person are interpreted as abnormal. The treatment aims to reduce symptoms and the possibility of disease recurrence. Aim: This study aimed to investigate the effectiveness
Nazanin Hoghoughi +4 more
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EPA guidance on assessment of negative symptoms in schizophrenia
European Psychiatry, 2021 BackgroundDuring the last decades, a renewed interest for negative symptoms (NS) was brought about by the increased awareness that they interfere severely with real-life functioning, particularly when they are primary and persistent.MethodsIn this ...
S. Galderisi +13 more
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European Psychiatry, 2021 Negative symptoms are considered a core feature of schizophrenia. They are present since the prodromal phase and tend to persist more than other psychopathological dimensions in the chronic stages.
A. Mucci +4 more
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Negative and Cognitive Symptoms of Schizophrenia: Are there Adequate Pharmacological Treatments?
European Psychiatry, 2022 Introduction The ongoing debate regarding the treatment efficacy for negative and cognitive symptoms in schizophrenia is a subject of continuous frustration among psychiatrists.
O. Vasiliu
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Adjunctive simvastatin treatment in schizophrenia patients; a double blind randomized and placebo controlled trial [PDF]
Journal of Preventive Epidemiology, 2022 Introduction: Statins such as simvastatin are recently introduced as agents that may have beneficial effects in schizophrenia regarding their prominent anti-inflammatory properties.
Somaieh Ashrafi +6 more
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Management of cognitive and negative symptoms in schizophrenia [PDF]
Mental Health Clinician, 2022 Currently available antipsychotics provide only modest benefit in managing the cognitive and negative symptoms of schizophrenia even though these symptoms are often the most impairing in patients daily lives.
Megan Maroney, PharmD, BCPP
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Negative symptoms - a real unmet need
European Psychiatry, 2022 Introduction Schizophrenia is frequently a chronic and disabling disorder, characterized by heterogeneous positive and negative symptoms. Negative symptoms are a major health concern and a core component of schizophrenia that account for a large part of
I. Soares Da Costa, R. Moreira
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Frontiers in Psychiatry, 2021 Objective: The relationship between negative symptoms and neurocognitive performance in schizophrenia is well documented, but the mechanism of these connections remains unclear.
Paweł Wójciak +4 more
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Relationship between Disability and Psychopathology Severity in Subjects having Acute Exacerbation of Schizophrenia on Treatment over three Month’s Duration [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Schizophrenia is a disorder which has a chronic course frequently with subjects having significant disability. Understanding what the symptoms during initial period are, which predict level of disability in future would be useful.
Praveen Arathil +1 more
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