Results 51 to 60 of about 480,384 (278)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Negative Thermal Expansion Coefficient of Graphene Measured by Raman Spectroscopy

open access: yes, 2011
The thermal expansion coefficient (TEC) of single-layer graphene is estimated with temperature-dependent Raman spectroscopy in the temperature range between 200 and 400 K.
Allen M. J.   +43 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Ionic conduction and negative thermal expansion of (H3O)Zr2(PO4)3

open access: yesStudies in Science and Technology
(NH4)Zr2(PO4)3 powder synthesized by hydrothermal reaction was heat-treated at 600 °C to obtain HZr2(PO4)3 powder, which was then autoclaved in deionized water at 150 °C to prepare (H3O)Zr2(PO4)3 powder.
Susumu Nakayama   +4 more
doaj   +1 more source

Negative thermal expansion in functional materials: controllable thermal expansion by chemical modifications

open access: yesChemical Society Reviews, 2015
Negative thermal expansion is an intriguing property of functional materials, which will give new phenomena and mechanisms for future studies.
Jun, Chen   +3 more
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Negative thermal expansion in the plateau state of a magnetically-frustrated spinel [PDF]

open access: yes, 2019
We report on negative thermal expansion (NTE) in the high-field, half-magnetization plateau phase of the frustrated magnetic insulator CdCr2O4. Using dilatometry, we precisely map the phase diagram at fields of up to 30T, and identify a strong NTE ...
Bobel, A.   +8 more
core   +3 more sources

Modifying Thermal Expansion of Polymer Composites by Blending with a Negative Thermal Expansion Material

open access: yesMacromolecular Materials and Engineering, 2007
AbstractLarge positive thermal expansion in polymers is one of the major drawbacks in using polymers in applications where the sample dimensions play an important role. In this paper, we report a method to vary the thermal expansion of PMMA‐based polymer composites by blending with a negative thermal expansion material, PbTiO3.
Chandra, A.   +4 more
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Origin of the Giant Negative Thermal Expansion in Mn3(Cu0.5Ge0.5)N

open access: yesAdvances in Condensed Matter Physics, 2012
The giant negative thermal expansion in the Ge-doped antiperovskite Mn3CuN compound is theoretically studied by using the first principles calculations. We propose that such a negative thermal expansion property is essentially attributed to the magnetic ...
B. Y. Qu, H. Y. He, B. C. Pan
doaj   +1 more source

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