Results 111 to 120 of about 1,297,038 (311)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Updated Trends in Child Maltreatment, 2013. [PDF]
, 2015 New national data for 2013 show continued declines in child maltreatment, after a one year discontinuity (2012) in which some rates briefly increased.
Finkelhor, David +2 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Abuse and Neglect of Animals and People, An Update [PDF]
, 2017 Veterinarians have noticed for quite some time that individuals who mistreat their animals may not stop there, carrying over their behavior to spouses, parents and others.
Ansello, Edward F.
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
El recuerdo de la Primera Guerra Mundial en los antiguos territorios del imperio austrohúngaro
Comillas Journal of International Relations, 2015 En el imperio austrohúngaro inevitablemente emergió una experiencia colectiva de la Gran Guerra. Sin embargo, la disolución repentina del imperio de los Habsburgo y las hostilidades inmediatas entre sus estados sucesores implicaron que nunca se llegó a ...
Christopher Brennan
doaj
We provide laboratory evidence that people neglect skewness resulting from compound shocks.Skewnes, belief biases, binomial ...
Georg Weizsäcker +2 more
core
Non-locality and Intermittency in 3D Turbulence
, 2001 Numerical simulations are used to determine the influence of the non-local and local interactions on the intermittency corrections in the scaling properties of 3D turbulence.
Dubrulle, B. +2 more
core +1 more source