Results 121 to 130 of about 1,307,822 (311)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
We provide laboratory evidence that people neglect skewness resulting from compound shocks.Skewnes, belief biases, binomial ...
Georg Weizsäcker +2 more
core +3 more sources
Updated Trends in Child Maltreatment, 2013. [PDF]
, 2015 New national data for 2013 show continued declines in child maltreatment, after a one year discontinuity (2012) in which some rates briefly increased.
Finkelhor, David +2 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Total Estimated Cost of Child Abuse and Neglect in the United States [PDF]
, 2007 Outlines the direct and indirect costs of addressing the physical, emotional, social, and cognitive impact of abuse and neglect on the victims, including health care, child welfare services, law enforcement, special education, and lost ...
Ching-Tung Wang, John Holton
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The Importance of Lens Galaxy Environments
, 2004 While many strong gravitational lens galaxies are suspected to lie in groups or clusters of galaxies, environmental effects in lens models are often unconstrained and sometimes ignored. We show that this creates significant biases in a variety of lensing
Ann I. Zabludoff +11 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A role for adverse childhood experiences and depression in preeclampsia
Journal of Clinical and Translational ScienceIntroduction: Adverse childhood experiences (ACEs) are a measure of childhood adversity and are associated with life-long morbidity. The impacts of ACEs on peripartum health including preeclampsia, a common and dangerous hypertensive disorder of ...
Monica Myers +9 more
doaj +1 more source
Maltreated children in the Looked After System: a comparison of outcomes for those who go home and those who do not [PDF]
, 2010 This project focuses on the consequences of decisions to reunify children who had entered the looked-after system for abuse or neglect. It compares the progress and outcomes of a sample of maltreated children who either went home or remained in the ...
Biehal, N +3 more
core