Results 61 to 70 of about 180,065 (263)

Reasons for the homelessness and neglect growth in the USSR in the 1940s

Известия высших учебных заведений. Поволжский регион: Гуманитарные науки, 2022
Background. The relevance of the chosen topic is determined by the need to study the causes of the homelessness and neglect growth in the USSR in the 1940s (the war and post-war period), since the future development of any society is largely determined
N.V. Semina
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

"Mirror agnosia" in a patient with right occipitotemporal infarct

Annals of Indian Academy of Neurology, 2006
We report the clinical profile and investigation of K, a patient suffering from agnosia for the concept of "mirrors". Normal people rarely confuse a mirror image for the real image.
Menon Bijoy, Shanbhogue K, Mutharasu C, Gopinathan S, Balasubramanian S, Chandramohan, Kingsly Jebasingh, Jawahar M   +7 more
doaj  

Not the Root of the Problem—Hair Cortisol and Cortisone Do Not Mediate the Effect of Child Maltreatment on Body Mass Index

Frontiers in Psychiatry, 2020
BackgroundExperiencing maltreatment during childhood exerts substantial stress on the child and increases the risk for overweight and obesity later in life.
Katharina Pittner, Katharina Pittner, Katharina Pittner, Renate S. M. Buisman, Renate S. M. Buisman, Renate S. M. Buisman, Lisa J. M. van den Berg, Lisa J. M. van den Berg, Laura H. C. G. Compier-de Block, Laura H. C. G. Compier-de Block, Marieke S. Tollenaar, Marieke S. Tollenaar, Marian J. Bakermans-Kranenburg, Marinus H. van IJzendoorn, Marinus H. van IJzendoorn, Bernet M. Elzinga, Bernet M. Elzinga, Lenneke R. A. Alink, Lenneke R. A. Alink   +18 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Neglected filoviruses [PDF]

FEMS Microbiology Reviews, 2016
(Uploaded by Plazi for the Bat Literature Project) Eight viruses are currently assigned to the family Filoviridae. Marburg virus, Sudan virus and, in particular, Ebola virus have received the most attention both by researchers and the public from 1967 to 2013.
Robin, Burk, Laura, Bollinger, Joshua C, Johnson, Jiro, Wada, Sheli R, Radoshitzky, Gustavo, Palacios, Sina, Bavari, Peter B, Jahrling, Jens H, Kuhn   +8 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Clinical TVA-based studies: a general review

Frontiers in Psychology, 2015
In combination with whole report and partial report tasks, the Theory of Visual Attention (TVA) can be used to estimate individual differences in five basic attentional parameters: The visual processing speed, the storage capacity of visual short-term ...
Thomas eHabekost
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source