Results 71 to 80 of about 177,944 (262)

Prevalence and associated factors of adolescent psychological abuse, neglect in Western China a multi-center cross-sectional study

European Journal of Psychotraumatology
Background: The western region of China has a dense population, relatively underdeveloped economy, and a significant number of left-behind children. Currently, the prevalence of adolescent psychological abuse, neglect, and the factors associated with ...
Cen Lin, Xiaohong Ren, Mengqin Dai, Yuhang Wu, Lu Pan, Yuqin Song, Yu Cen, Qiuyue Fan, Cailin Xie, Jiarui Shao, Ying Chen, Yao Wang, Jiaming Luo   +12 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Forensic Entomological Examinations for Animal Welfare Offices under Suboptimal Preservation Conditions

Forensic Sciences
A female dog had allegedly been alive one day before its death. The veterinary office thought about accusing the dog’s owner for animal cruelty and commissioned forensic entomological expertise for the calculation of the time of insect colonization on ...
Kristina Baumjohann, Mark Benecke
doaj   +1 more source

Clinical TVA-based studies: a general review

Frontiers in Psychology, 2015
In combination with whole report and partial report tasks, the Theory of Visual Attention (TVA) can be used to estimate individual differences in five basic attentional parameters: The visual processing speed, the storage capacity of visual short-term ...
Thomas eHabekost
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Magie de Noël à la résidence intermédiaire : un conte urbain

BioéthiqueOnline, 2013
The following urban tale is a fiction inspired by a tragic event that took place in Montreal in December 2009. This urban tale illustrates ethical issues representing key questions related to the protection of vulnerable populations, that is ...
Laliberté, Maude
doaj  

Lifetime Experience of Childhood Abuse and Neglect Among High School Students at Debre Tabor Town, South Gondar Zone, Northwest Ethiopia: An Institution-Based Cross-Sectional Study

Journal of Multidisciplinary Healthcare, 2023
Demewoz Kefale,1 Mastewal Endalew,2 Worku Necho Asferie,3 Solomon Demis,3 Tigabu Munye,4 Yohannes Tesfahun,5 Amare Simegn,6 Mahilet Wondim,7 Amare Kassaw,1 Gashaw Kerebeh,1 Demeke Mesfin Belay,1 Binyam Minuye,3 Shegaw Zeleke4 1Department of Pediatrics ...
Kefale D, Endalew M, Asferie WN, Demis S, Munye T, Tesfahun Y, Simegn A, Wondim M, Kassaw A, Kerebeh G, Belay DM, Minuye B, Zeleke S   +12 more
doaj  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source