Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine
Advanced Science, EarlyView.This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan +24 more
wiley +1 more source
A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions
Advanced Science, EarlyView.This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies +14 more
wiley +1 more source
Advanced Science, EarlyView.Computational annotation of various tissue types in heterogeneous samples such as colorectal cancer liver metastasis (CRLM) using spatial autocorrelation analysis on non‐destructive mid‐infrared (MIR) imaging data enabled correlative multimodal mass spectrometry imaging (MSI) for spatial investigation of lipid tumor marker candidates. The method can be
Miriam F. Rittel +12 more
wiley +1 more source
COVID-19 vaccines and the pandemic: lessons learnt for other neglected diseases and future threats. [PDF]
BMJ Glob Health, 2023 Hotez PJ +7 more
europepmc +1 more source
Correction: Buruli Ulcer in Cameroon: The Development and Impact of the National Control Programme. [PDF]
PLoS Neglected Tropical Diseases, 2016 PLOS Neglected Tropical Diseases Staff
doaj +1 more source
China's innovation and research contribution to combating neglected diseases: a secondary analysis of China's public research data. [PDF]
Glob Health Res Policy, 2023 Ma J +5 more
europepmc +1 more source
Can medical products be developed on a non-profit basis? Exploring product development partnerships for neglected diseases [PDF]
, 2017 Reliance on market forces can lead to underinvestment in social welfare enhancing innovation. The lack of new medical products in the area of neglected diseases is a case in point.
Foray, D. +3 more
core
Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay
Advanced Science, EarlyView.This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao +6 more
wiley +1 more source
Correction: Pyrethroid Treatment of Cattle for Tsetse Control: Reducing Its Impact on Dung Fauna. [PDF]
PLoS Neglected Tropical Diseases, 2015 PLOS Neglected Tropical Diseases Staff
doaj +1 more source