Results 191 to 200 of about 180,358 (308)

Taking the neglected out of neglected tropical diseases [PDF]

The Lancet Global Health, 2020
openaire   +3 more sources

Hand eczema: a ‘neglected’ disease [PDF]

Journal of the European Academy of Dermatology and Venereology, 2019
P. Elsner, T. Agner
openaire   +3 more sources

Machine Learning‐Enhanced Random Matrix Theory Design for Human Immunodeficiency Virus Vaccine Development

Advanced Intelligent Discovery, EarlyView.
This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah, Muhammad Zulqarnain Zeb, Muhammad Husnain Zeb, Babar Shabbir   +3 more
wiley   +1 more source

Interventions for Neglected Diseases Caused by Kinetoplastid Parasites: A One Health Approach to Drug Discovery, Development, and Deployment. [PDF]

Pharmaceuticals (Basel)
Ebiloma GU, Alhejeli A, de Koning HP.
europepmc   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Collaborative Synthesis for Neglected Diseases through the Open Synthesis Network: Structure-Activity Relationships of Arylaminopyrazoles as Chagas Disease Treatments. [PDF]

ACS Infect Dis
Abdulai Z, Agbo N, Anderson JI, Astley F, Chan B, Atkinson-Evans O, Avelar JL, Aparecida-Silva C, Bhardwaj KD, Bowley WJ, Breitkreuz N, Canby R, Cartwright E, Clifford C, Cordell SA, Donker WJ, Driscoll J, Grady M, Higginbotham L, Hsu D, Hutchinson J, Imberg L, Jackson HF, Johns F, Jones E, Kalinin DV, Kardeşler C, Keal A, Keel L, Kim S, Knight P, Ködel JF, Kumeta L, Lee H, Le Roy S, Maccarone R, Mahmud M, Martin M, Nguyen I, Nolan CJ, Noyes L, Ntuwa ANW, Obarska W, Oldham O, Onyiuke E, Otter J, Page H, Patel D, Reid K, Samaddar K, Shabbir SM, Shevlin P, Sinclair-Wright C, Smithies A, Thomson AS, Tinker J, Uner A, Van Pelt N, Waddell E, Wagwa H, Walthorne C, Warner S, Winge T, Sum Wong N, Wysocki LJ, Yong CA, Zaheen Z, Matheeussen A, Caljon G, Amewu R, Bertram A, Biersack B, Friel C, Lima LM, Smith C, Wünsch B, Perry B, Cruz LR, Nortcliffe A.   +78 more
europepmc   +1 more source

Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art

Advanced Intelligent Discovery, EarlyView.
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser, Haseeb Muhammad, Junaid Younas, Gillian Lovell, Bianca Migliori, Andreas Dengel, Sheraz Ahmed   +6 more
wiley   +1 more source

Attention to the Registry of Neglected Diseases: Idiopathic Granulomatous Mastitis as an Example. [PDF]

Int J Health Policy Manag
Alipour S, Zafarghandi M, Group II.
europepmc   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

AI-powered drug discovery for neglected diseases: accelerating public health solutions in the developing world. [PDF]

J Glob Health
Nishan MDNH.
europepmc   +1 more source