Results 211 to 220 of about 164,582 (264)

Biopharmaceutical optimization in neglected diseases for paediatric patients by applying the provisional paediatric biopharmaceutical classification system. [PDF]

Br J Clin Pharmacol, 2018
Del Moral Sanchez JM, Gonzalez-Alvarez I, Cerda-Revert A, Gonzalez-Alvarez M, Navarro-Ruiz A, Amidon GL, Bermejo M.   +6 more
europepmc   +1 more source

Developing a critical caste analysis within information science and technology: A research review: An Annual Review of Information Science and Technology (ARIST) paper

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Caste—an ascriptive social hierarchy in South Asia and its diaspora—is a globalized phenomenon. Recent caste‐based discrimination, particularly in technology companies and anti‐caste efforts to address it, has compelled academia, policy, and the technology industry to better understand contemporary mechanics of caste.
Nayana Kirasur, Britt Paris
wiley   +1 more source

Developing new health technologies for neglected diseases: a pipeline portfolio review and cost model. [PDF]

Gates Open Res, 2018
Young R, Bekele T, Gunn A, Chapman N, Chowdhary V, Corrigan K, Dahora L, Martinez S, Permar S, Persson J, Rodriguez B, Schäferhoff M, Schulman K, Singh T, Terry RF, Yamey G.   +15 more
europepmc   +1 more source

A Modified Anatomical All‐Inside Double‐Bundle Anterior Cruciate Ligament Reconstruction Technique

Arthroscopy Techniques, EarlyView.
Abstract Arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) is the standard surgical treatment for ACL injuries and is most commonly performed using anatomical single‐bundle (SB) or double‐bundle (DB) techniques. With the development of the all‐inside technique, the all‐inside SB technique using socket‐based tunnels and cortical ...
Hanting Yi, Hongyu Li, Yaoqiang Chen, Wen Yang, Wentao Zhang, Mengjun Ma, Yundan Jiang   +6 more
wiley   +1 more source

The Impact of Ken Warren's Leadership of the Rockefeller Foundation's Great Neglected Diseases Program on the Future of Malaria Research. [PDF]

Am J Trop Med Hyg, 2017
Miller LH.
europepmc   +1 more source

Avoiding Tunnel Collisions in Knee Posterolateral Corner Reconstructions: The “Versailles” Technique

Arthroscopy Techniques, EarlyView.
Abstract The fibular collateral ligament, the popliteo‐fibular ligament and the popliteus tendon are the 3 main elements of the posterolateral corner (PLC), which is regularly injured in case of multiligament knee injuries. PLC reconstruction is recommended over repair in a large most situations, including acute cases.
Simon Corsia, Joseph Attas, Az‐Eddine Djebara, Philippe Boisrenoult, Nicolas Pujol   +4 more
wiley   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Impact of parameter settings on the estimation of drug exposure with the individualized dispensing patterns method

British Journal of Clinical Pharmacology, EarlyView.
Aim To assess the impact of parameter settings when using the individualized dispensing patterns (IDP) method to estimate exposure duration from dispensing data. Methods We conducted a cohort study using a 2% representative sample of the French healthcare insurance database from 2013 to 2022.
Laëtitia Gosselin, Clara Lévy, Noémie Sève, Thierry Blanchon, Marianne Sarazin, Louise Rossignol, Maryse Lapeyre‐Mestre, Nathanaël Lapidus, Olivier Steichen   +8 more
wiley   +1 more source