Results 61 to 70 of about 1,335,420 (346)

When does the evoluted set have negligible boundary? [PDF]

, 2021
The evoluted set at time T is the union of all images of an initial set A via the flow at times t ∈ (0, T). Its regularity is for interest for control, being the attainable set in several relevant examples.We first show that it is not sufficient for A to
Francesco Rossi, Boarotto F., Boarotto, Francesco, Rossi, Francesco, Francesco Boarotto, Rossi F.   +5 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Is the smokers exposure to environmental tobacco smoke negligible?

Environmental Health, 2010
Background Very few studies have evaluated the adverse effect of passive smoking exposure among active smokers, probably due to the unproven assumption that the dose of toxic compounds that a smoker inhales by passive smoke is negligible compared to the ...
Valerio Federico, Stella Anna, Piccardo Maria Teresa   +2 more
doaj   +1 more source

Negligible isotopic fractionation of nitrogen within temperate Zostera spp. meadows [PDF]

Biogeosciences, 2018
Seagrass meadows form an ecologically important ecosystem in the coastal zone. The 15N∕14N ratio of seagrass is commonly used to assess the extent to which sewage-derived nitrogen may be influencing seagrass beds.
D. G. Russell, W. W. Wong, P. L. M. Cook
doaj   +1 more source

PROFESSIONAL NEGLIGENCE [PDF]

Australian and New Zealand Journal of Ophthalmology, 1988
AbstractIn the last 5 years there has been an extraordinary increase in negligence actions against South Australian ophthalmologists. This paper considers the reasons, in particular those changes in the interpretation of the law which have made doctors vulnerable.
openaire   +2 more sources

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Emission of primary microplastics in mainland China: Invisible but not negligible.

Water Research, 2019
Primary microplastics are mostly produced as part of the daily plastic product use. The emission process is often invisible but poses potential ecological hazards. Thus, primary microplastics deserve public attention.
Teng Wang, Baojie Li, X. Zou, Ying Wang, Ya-Li Li, Yong-Jiang Xu, Long-Jiang Mao, Chuchu Zhang, Wen-Wen Yu   +8 more
semanticscholar   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Peer review of the pesticide risk assessment for the active substance isoxaflutole in light of negligible exposure data submitted

EFSA Journal, 2017
The conclusions of EFSA following the peer review of the initial risk assessment carried out by the competent authority of the rapporteur Member State, Italy, for the pesticide active substance isoxaflutole are reported.
European Food Safety Authority (EFSA), Alba Brancato, Daniela Brocca, Arianna Chiusolo, Daniele Court Marques, Federica Crivellente, Chloe De Lentdecker, Marcella De Maglie, Mark Egsmose, Zoltan Erdos, Gabriella Fait, Lucien Ferreira, Marina Goumenou, Luna Greco, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Renata Leuschner, Christopher Lythgo, Jose Oriol Magrans, Paula Medina, Ileana Miron, Tunde Molnar, Alexandre Nougadere, Laura Padovani, Juan Manuel Parra Morte, Ragnor Pedersen, Hermine Reich, Angela Sacchi, Miguel Santos, Rositsa Serafimova, Alois Stanek, Juergen Sturma, Jose Tarazona, Andrea Terron, Benedicte Vagenende, Alessia Verani, Laura Villamar‐Bouza   +37 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source