Results 71 to 80 of about 1,335,420 (346)

Peer review of the pesticide risk assessment for the active substance bromoxynil in light of negligible exposure data submitted

open access: yesEFSA Journal, 2018
The conclusions of EFSA following the peer review of the initial risk assessment carried out by the competent authority of the rapporteur Member State France for the pesticide active substance bromoxynil are reported.
European Food Safety Authority (EFSA)   +49 more
doaj   +1 more source

Negligible Toxicokinetic Differences of Glyphosate by Different Vehicles in Rats

open access: yesToxics, 2023
Glyphosate is a non-selective herbicide. Although glyphosate is not acutely toxic, the intake of glyphosate-based herbicides has caused many accidents. Some studies have suggested that surfactants might be the cause.
Yu-Jin Kim, Nitin Nitin, Kyu-Bong Kim
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Development and application of an oedometer with negligible side-wall friction for rockfill materials

open access: yesYantu gongcheng xuebao, 2022
The oedometer is one of the most commonly used apparatuses to investigate the long-term deformation behaviors of rockfill materials. However, the side-wall friction restrains its application.
WANG Long 1, ZHU Jun-gao 1, YUAN Jun-ping 1, LU Yang-yang 2
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

A STROKE OF NEGLIGENCE

open access: yesRomanian Journal of Neurology, 2015
A 81-year-old female patient suffering from type II diabetes mellitus, atrial fibrillation, hypertension and who neglected taking any medication at home, was referred to our clinic from the "St. Pantelimon" Hospital, where she had been brought by her family one day earlier, because of severely altered state of consciousness.
Daniela Trasca   +2 more
openaire   +2 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Age is just a number

open access: yeseLife, 2018
The naked mole rat defies the Gompertz law and shows no sign of increased mortality risk as it gets older.
Hiram Beltrán-Sánchez, Caleb Finch
doaj   +1 more source

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