Results 71 to 80 of about 864,462 (313)
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Strategos, 2022 Insurgency and counterinsurgency, as modern forms of warfare, are presented in the paper as two phenomena that are actually present in all phases of human civilization.
Marija Bortek, Andrija Kozina
doaj
Untangling subsidies, supporting fisheries: the WTO fisheries subsidies debate and developing-country priorities [PDF]
, 2006 This paper examines, from the fishery perspective of a developing country, the current debate on the role of fisheries subsidies in the context of the negotiations relating to the General Agreement on Tariffs and Trade GATT) and the World Trade ...
Kurien, John
core
, 2015 Negotiations, a model of concurrency with multi party negotiation as primitive, have been recently introduced by J. Desel and J. Esparza. We initiate the study of games for this model.
Hoffmann, Philipp
core +2 more sources
Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane +19 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Increasing Use of “Negotiated” Instruments of European Competition Law Enforcement towards Foreign Companies [PDF]
Yearbook of Antitrust and Regulatory Studies, 2014 This paper considers the increasing use of “negotiated” instruments of European competition law (ECL) enforcement as illustrated by the example of the European Commission’s (EC) enforcement practice directed at firms of American and East Asian origin ...
Ewelina D. Sage
doaj
Arthritis Care &Research, EarlyView.Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg +20 more
wiley +1 more source
Arms Races and Negotiations [PDF]
A state which does not desire an arms race may nevertheless acquire new weapons if it believes another state will acquire them. If each state assigns some arbitrarily small probability to the event that the other state has a dominant strategy to acquire ...
Balinga, Sandeep, Sjostrom, Tomas
core +6 more sources
Arthritis Care &Research, EarlyView.Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández +10 more
wiley +1 more source