Results 61 to 70 of about 864,462 (313)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Managing Environmental Water Use Conflicts: International Experience
RUDN Journal of Political ScienceIn recent decades, there has been a considerable growth in the number of environmental conflicts worldwide, with environmental conflicts over water use standing out for their unique characteristics, causes, and challenges in resolution. Based on a number
Artur L. Demchuk
doaj +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Malinche and the Conquest of Mexico. An Attempt at Historical Reconstruction
Ибероамериканские тетрадиThe author sets forward a hypothesis of his own (though based on reliable sources) of the course of events that led to the subdual or, more exactly, to the loss of power of the Aztec Empire over what is now Mexico and the fall of the land under control ...
A. V. Sadikov
doaj +1 more source
Strategy and Tactics of International Mergers and Acquisitions [PDF]
International Economic Policy, 2011 The article reviews contemporary strategy and tactics issues in terms of international mergers and acquisitions, along with displaying cyclical waves of mergers and acquisitions over the last century as well as motivation thereof. Five strategies adhered
Denys Kiriakov
doaj
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Studia Universitatis Babeş-Bolyai. Studia Europaea, 2017 The volume Romania and the European way of life (2017), by professor Vasile Pușcaș, presents-without pretending to be exhaustive on the topic-a comprehensive analysis of the local, national, regional and global context of Romania's accession to the ...
Iulia Anamaria GHIDIU
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Time-lag i biznes. O pozaekonomicznych wyznacznikach parametrów ekonomicznych
Studia i Materiały, 2012 The system of law enactment in Poland is flawed. It should be based on consultations between the government and non-governmental communities and institutions. One of the tools of such consultations, i.e.
Marek Goliszewski
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
From Opinion 2/13 to the 2023 Draft Accession Agreement: The Chair’s Perspective
European Papers(Series Information) European Papers - A Journal on Law and Integration, 2024 9(2), 685-694 | Article | (Table of Contents) I. Introduction. – II. Basic principles in the negotiations. – III. Negotiating the issues deriving from Opinion 2/13. – III.1. EU-
Tonje Meinich
doaj +1 more source