Results 261 to 270 of about 1,455,539 (349)
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Neighborhood social fragmentation and cerebello-thalamo-cortical connectivity in youth at clinical high-risk for psychosis and healthy comparisons. [PDF]
Ku BS +13 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Single-cell spatial transcriptomic analysis of human skin anatomy. [PDF]
Restrepo P +24 more
europepmc +1 more source
Food availability in the heartland: effects of neighborhood race and income composition
Michael J. Miller
openalex +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Multilevel Predictors of Intervention Uptake and Postintervention Physical Activity Behaviors Among Churchgoing Latino Adults. [PDF]
Perez LG +7 more
europepmc +1 more source

