Molecular Diagnostics Update for the Emerging (If Not Already Widespread) Sexually Transmitted Infection Agent \u3cem\u3eMycoplasma genitalium\u3c/em\u3e: Just About Ready for Prime Time [PDF]
Mycoplasma genitalium is an important and emerging agent of sexually transmitted infection in females and males, carrying the potential for postinfection genital tract sequelae.
Erik, Munson
core +1 more source
ABSTRACT Problem Female genital mutilation/cutting (FGM/C) is harmful to physical, mental, and reproductive health, though the effect of this practice on a woman's HIV susceptibility is poorly understood. Despite the known associations of FGM/C with short‐term vaginal epithelial damage, neither genital inflammation nor the genital microbiome have been ...
James Pollock +19 more
wiley +1 more source
Objective To summarize the surveillance results of antibiotic resistance of Neisseria gonorrhoeae to 7 antibiotics (penicillin G, tetracycline, ciprofloxacin, spectinomycin, cefixime, ceftriaxone and Azithromycin) in Panyu District, Guangzhou, from 2018 ...
Huanxi LIANG +6 more
doaj +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]
Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X +6 more
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Bacterial Infections Role in Gynecological Cancers Development: Narrative Review
ABSTRACT Background Gynecological cancers are among the most common cancers in women that affect female reproductive organs. The most common gynecological cancers are ovarian, cervical, uterine/endometrial, vaginal, and vulvar cancer. Women's reproductive organs have a dynamic and relative microbial balance.
Robab Azargun +7 more
wiley +1 more source
Measurement and predictors of adherence in a trial of HSV suppressive therapy in Tanzania.
This study estimates adherence and identifies predictors of good adherence among 1305 Tanzanian women participating in a randomised, double-blind, placebo-controlled trial of HSV suppressive therapy to reduce HIV incidence or genital HIV shedding.
Baisley, Kathy +10 more
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Predominant porB1A and porB1B genotypes and correlation of gene mutations with drug resistance in Neisseria gonorrhoeae isolates in Eastern China [PDF]
Background Variations of porB1A and porB1B genes and their serotypes exist in Neisseria gonorrhoeae isolates from different geographical areas, and some site mutations in the porB1B gene correlate with drug resistance.
Aihua Sun +7 more
core +1 more source
Bacterial Extracellular Vesicles in Biomedical Research and Clinical Translation
Bacterial membrane vesicle biomedical applications. ABSTRACT Bacterial Extracellular Vesicles (bEVs) are lipid (single‐ or double‐bilayer) nanostructures secreted by virtually all bacteria that play fundamental roles in intercellular communication and have emerged as powerful, multifunctional tools in biomedicine. Their intrinsic ability to encapsulate
Alejandro Arce‐Rodríguez +2 more
wiley +1 more source
NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function [PDF]
The Rrf2 family transcription factor NsrR controls expression of genes in a wide range of bacteria in response to nitric oxide (NO). The precise form of the NO-sensing module of NsrR is the subject of controversy because NsrR proteins containing either ...
Al-Bassam, Mahmoud +12 more
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