LL‐37: Biological Mechanisms and Emerging Therapeutic Applications in Intestinal Disease
ABSTRACT Human cathelicidin peptide LL‐37 is encoded by the CAMP gene and plays a key role in innate immunity. It maintains intestinal homeostasis through antibacterial, immunomodulation, and tissue repair functions. This paper reviews the multiple functions of LL‐37 in the intestinal‐immune axis and its contribution to intestinal immune homeostasis. A
Qichao Liu, Peng Xu, Cheng Zhang
wiley +1 more source
Organism resembling Neisseria gonorrhoeae and Neisseria meningitidis [PDF]
A problem isolate resembling Neisseria gonorrhoeae and Neisseria meningitidis is reported. Growth and biochemical characteristics indicated the organism to be N. meningitidis, whereas serological characteristics indicated it to be N. gonorrhoeae. This vaginal isolate may be a genetically transformed gonococcus with the ability to utilize maltose ...
D S, Hodge +3 more
openaire +2 more sources
ABSTRACT Sexually transmitted infections (STIs) remain a major global health threat. A comprehensive assessment of their epidemiological features and future trajectories is essential for informing targeted public health policies and achieving international control targets.
Baigong Feng +5 more
wiley +1 more source
A human pathogen, \textit{Neisseria gonorrhoeae} (NG), moves on surfaces by attaching and retracting polymeric structures called Type IV pili. The \textit{tug-of-war} between the pili results in a two-dimensional stochastic motion called \textit ...
Banerjee, Varsha +3 more
core +1 more source
Neisseria gonorrhoeae false-positive result obtained from a pharyngeal swab by using the roche cobas 4800 CT/NG assay in New Zealand in 2012 [PDF]
The Roche cobas 4800 CT/NG assay is a commonly used commercial system for screening for Neisseria gonorrhoeae infection, and previous studies have shown the method to be highly sensitive and specific for urogenital samples. We present the first confirmed
A. Upton +13 more
core +1 more source
The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria
ABSTRACT Serine acetyltransferase (CysE) is a member of the left‐handed β‐helix family of acetyltransferases that catalyze the rate limiting step in de novo cysteine biosynthesis. There are two isoforms of CysE that differ in length, with the shorter isoform lacking approximately 76 amino acids at the N‐terminus of the protein from the serine ...
Keely E. A. Oldham +3 more
wiley +1 more source
Diagnosis of Neisseria gonorrhoeae among pregnant women by culture method and PCR on cppB gene
Background: Neisseria gonorrhoeae is a human obligate pathogen and the etiological agent of gonorrhea. Health irreparable complications resulting from gonorrhea disease occur mainly in pregnant women and neonates.
Jalal Mardaneh +4 more
doaj
High Prevalence of Mutations in Quinolone-resistance-determining Regions and mtrR Loci in Polyclonal Neisseria gonorrhoeae Isolates at a Tertiary Hospital in Southern Taiwan [PDF]
Background/PurposeThe emergence of multidrug-resistant Neisseria gonorrhoeae is a great challenge in controlling gonorrhea. This study was conducted to survey the prevalence of molecular mechanisms of antimicrobial resistance among 45 clinical isolates ...
Chen, Po-Lin +10 more
core +2 more sources
AI‐Enabled Imaging for Pathogen Detection Under Stress Conditions: A Systematic Review
ABSTRACT Advances in pathogen detection that incorporate artificial intelligence (AI) may capture microbial signals under challenging environmental conditions that traditional methods miss. This systematic review evaluates the application, performance, and methodological characteristics of AI‐enabled imaging for pathogen detection, including its impact
MeiLi Papa +3 more
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