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Postgenomics ofNeisseria meningitidis: an update [PDF]

open access: possibleExpert Review of Proteomics, 2009
Neisseria meningitidis infection represents a major life-threatening bacterial disease worldwide. Genomics has revolutionized every aspect of the field of microbiology. As a consequence of genome sequencing, the postgenomic era commenced 15 years ago. Comparative genomics, functional genomics and proteomics, as well as a combination of these techniques,
BERNARDINI, GIULIA   +3 more
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Neisseria meningitidis, a Respiratory Pathogen?

Journal of Infectious Diseases, 1970
The literature on meningococcal disease in the past few years has been dominated by discussions of sulfonamide resistance, prophylaxis, intravascular coagulation in fulminant disease, and determination of additional serological groups. This paper considers yet another facet, namely, the role of the meningococcus in respiratory disease and bacterial ...
John D. Hamilton   +2 more
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Dissemination ofNeisseria meningitidis

New England Journal of Medicine, 2011
Infection of the mucosal epithelium of the nasopharynx by Neisseria meningitidis can lead to systemic invasion, resulting in fulminant sepsis and meningitis. A recent study divulges a molecular event relevant to the dissemination of the bacterium.
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Exogenous Neisseria meningitidis Endophthalmitis

American Journal of Ophthalmology, 1997
To report a case of Neisseria meningitidis endophthalmitis in association with a leaking filtering bleb and to consider antibiotic prophylaxis of those people with whom the patient had contact.We treated an 81-year-old man who had a chronic, leaking filtering bleb and who developed exogenous N meningitidis endophthalmitis.N meningitidis endophthalmitis
Michael D. Bennett   +4 more
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Hemagglutination by Neisseria meningitidis

Canadian Journal of Microbiology, 1981
The direct agglutination of erythrocytes by Neisseria meningitidis was studied as a marker for adherence. Hemagglutination (HA) was studied by slide test (5-min incubation) and by dilutions in microtitre plates (20-h incubation). Meningococci that were freshly isolated from subjects agglutinated only human cells by slide test but human, dog, rabbit ...
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Molecular epidemiology of neisseria meningitidis

Frontiers in Bioscience, 2003
Neisseria meningitidis poses a major disease burden on human beings. Meningococcal typing has a longstanding tradition for epidemiological surveillance of the disease. Genetic and antigenetic variability resulting from horizontal genetic exchange has been exploited for this purpose.
Ulrich Vogel, Heike Claus
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Neisseria meningitidis

2019
This volume provides methods to analyze the meningococcus and its interactions with biologically relevant host cells and sites, to interrogate the population structure and biology of the meningococcus that defines its capacity to cause disease, and to aid in vaccine development and surveillance.
Hollingshead, S   +3 more
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Neisseria meningitidis Vaccines

2003
Meningococcal disease, both endemic and epidemic, remains a major cause of meningitis in many countries. Protective immunity is mediated primarily by bactericidal antibodies against the capsular polysaccharides as well as against outer membrane protein and lipopolysaccharide components.
Margaret C. Bash, Carl E. Frasch
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Urethritis caused by Neisseria meningitidis

Journal of Clinical Microbiology, 1980
A glucose-negative group B strain of Neisseria meningitidis isolated from a meningitis case is described. A brief review of Neisseria identification procedures is also presented.
B A Nolan, A L Gandelman, J J Karolus
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Neisseria meningitidis Conjunctivitis in Children

American Journal of Ophthalmology, 1987
We examined two children from the same family who had purulent conjunctivitis. Isolates of Neisseria species were obtained from eye cultures and Gram stain of conjunctival scrapings disclosed many gram-negative intracellular diplococci. Colony structure and growth characteristics of the organism with subsequent carbohydrate fermentation tests and ...
Fatma Al-Mutlaq   +2 more
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