Results 51 to 60 of about 11,952,562 (245)

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

open access: yesAngewandte Chemie, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang   +15 more
wiley   +2 more sources

Thinking social sciences from Latin America at the epochal change

open access: yesCuestiones de Sociología, 2016
From the legacy of an original disciplinary approach, as the Dependence theory and its Marxian critics, or the neo-structural economic theory founded by The Economic Commission for Latin America (ECLA), the Latin-American social sciences deny the Anglo ...
Jaime Antonio Preciado Coronado
doaj  

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen   +10 more
wiley   +1 more source

El enfoque espacial en la Economía Política

open access: yesEconómica, 1959
After a brief introduction dealing in big lines with the economic thought of the classical and neo-classical schools the author proceeds to analyses the progress achieved in the last 25 years.
Oreste Popescu
doaj  

From Protectionism to Neo-Protectionism: New Dimensions of Liberal Regulation [PDF]

open access: yesInternational Economic Policy, 2017
The article summarizes the main concepts of the policy of protectionism. It was proved that the shaded or semi-open nature of protectionism of the 21st century model does not fall under classical manifestations of protectionism recorded in the WTO ...
Panchenko Volodymyr, Reznikova Nataliia
doaj  

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

open access: yesAdvanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan   +9 more
wiley   +1 more source

The maximal subgroups of the classical groups in dimension 13, 14 and 15 [PDF]

open access: yes, 2015
One might easily argue that the Classification of Finite Simple Groups is one of the most important theorems of group theory. Given that any finite group can be deconstructed into its simple composition factors, it is of great importance to have a ...
Anna Katharina Schröder   +1 more
core   +2 more sources

Tendencias actuales del pensamiento económico

open access: yesEconómica, 1958
After a brief introduction dealing in big lines with the economic thought of the classical and neo-classical schools the author proceeds to analyses the progress achieved in the last 25 years.
Oreste Popescu
doaj  

The balance of payments constraint as an explanation of the international growth rate differences

open access: yesPSL Quarterly Review, 2014
The neo-classical approach to the question of why growth rates differ between countries concentrates on the supply side of the economy using the concept of the production function. While this approach is fruitful, it does little to explain why the growth
A.P. THIRLWALL
doaj   +1 more source

The Aggregate Demand, Aggregate Supply, and Endogenous Growth: A Synthetic neo-Kaleckian Model [PDF]

open access: yes
This paper develops a neo-Kaleckian endogenous growth model that incorporates aggregate supply - demand balance and balance between labor force and employment growth.
Thomas I. Palley
core  

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