Results 61 to 70 of about 11,952,562 (245)

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Il vincolo della bilancia dei pagamenti come elemento di spiegazione delle differenze internazionali dei tassi di sviluppo

Moneta e Credito, 2014
The neo-classical approach to the question of why growth rates differ between countries concentrates on the supply side of the economy using the concept of the production function. While this approach is fruitful, it does little to explain why the growth
A.P. THIRLWALL
doaj   +1 more source

MODIFYING THE NEO-CLASSICAL APPROACH TO TECHNOLOGY ADOPTION WITH BEHAVIORAL SCIENCE MODELS [PDF]

The dualistic nature of humans has been recognized for centuries. The intriguing question is the extent to which the human being with her/his display of concern for others can simultaneously act as an egoist, the latter being descriptive of the homo ...
Lynne, Gary D.
core  

Neo-sex chromosome homology.

, 2018
A. Global neo-sex chromosome alignments show large homologous blocks between the neo-sex chromosomes along the long arm of the Y/neo-Y. B and C. Zoom-in of selected homologous regions along the neo-sex chromosomes.
Doris Bachtrog (1163), Kevin H.-C. Wei (5570777), Matthew J. Nalley (5570780), Shivani Mahajan (450873), Lauren Gibilisco (3389276)   +4 more
core   +1 more source

Integrated O2 and H2 Gas Therapy via Microneedle‐Assisted Photocatalytic Water Splitting for Accelerating Diabetic Full‐Thickness Skin Wound Healing

Advanced Science, EarlyView.
A concept of integrated O2 and H2 gas therapy is achieved using a gas‐producing material. PMP nanoparticles, fabricated from platinum, MIL‐101(Fe)‐NH2, and phosphotungstic acid, are integrated into bilayer gelatin methacryloyl microneedles for transdermal delivery. These microneedles enable integrated O2 and H2 gas therapy and promote wound healing via
Zesheng Chen, Yanchao Yu, Xingyuan Xiao, Wenwen Cheng, Ye Yang, Zhengyao Zhang, Wang Wang, Zhijun Zhou, Weikang Hu, Xiaolong Wang, Bing Li, Kwang Leong Choy, Yun Chen, Zijian Wang   +13 more
wiley   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source

Quantum Economics: A Systematic Literature Review [PDF]

SocioEconomic Challenges
In the 21st century, various socio-economic crises have revealed that traditional economic science and (neo)classical thinking are unable to explain all the complexity of current economic problems, therefore the application of more complex and non ...
Thomas Holtfort, Andreas Horsch
doaj   +1 more source

Microfoundations: a decisive dividing line between Keynesian and new classical macroeconomics? [PDF]

It is often argued that what marks the difference between Keynesian macroeconomics and new classical macroeconomics (the first installment of dynamic stochastic general equilibrium models) is the presence of microfoundations.
Michel DE VROEY
core  

The delegation of power: Neo-Assyrian bureau seals [PDF]

, 2008
Bureau seals are an innovation of the Assyrian administration to cope with the delegation of power that running a world empire demanded. By placing some bureau seals in their historical context we find indications that these seal types were introduced ...
Radner, K
core  

Last Empress Fiction and Asian Neo-Victorianism [PDF]

, 2019
This article claims that ‘Last Empress’ fiction about the Empress Dowager Cixi reveals the postcolonial ethics of Anglophone neo-Victorianism. ‘Last Empress’ texts naturally tend to be bookended by the narrative of a naïve yet ambitious teenage
Ho, HLE
core   +1 more source