Comparative outcomes of neoadjuvant immunochemotherapy versus neoadjuvant chemoradiotherapy in locally advanced thoracic esophageal squamous cell carcinoma: a target trial emulation. [PDF]
Li Z +9 more
europepmc +1 more source
Non‐Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy?
ABSTRACT Background In patients with locally advanced, non‐metastatic oropharyngeal squamous cell carcinoma (OPSCC), surgery‐based and nonsurgical treatment approaches have not been adequately compared in randomized Phase III clinical trials. Current clinical guidelines recommend various surgical and nonsurgical strategies across disease stages for ...
Primož Strojan +12 more
wiley +1 more source
Influence of KRAS mutation subtypes on response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: meta-analysis. [PDF]
Sadien ID +5 more
europepmc +1 more source
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) is frequently diagnosed at advanced stages and has historically been associated with poor outcomes. Immune checkpoint inhibition has transformed the therapeutic landscape, offering durable responses in recurrent, metastatic, and locally advanced disease.
Carol R. Bradford +5 more
wiley +1 more source
Weekly measurement of HMGB1 during neoadjuvant chemoradiotherapy in rectal cancer patients: correlations with MRI response and ctDNA. [PDF]
Eckert F +8 more
europepmc +1 more source
ABSTRACT Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. We conducted a systematic review and meta‐analysis of studies that developed, validated, or updated clinical prognostic tools to predict survival in adults with primary GIST, identifying 47 eligible studies (38 development and 9 ...
Alice Zhu +7 more
wiley +1 more source
A simple MRI/PET-derived index predicts relapse-free survival after neoadjuvant chemoradiotherapy in locally advanced rectal cancer. [PDF]
Shioi I +15 more
europepmc +1 more source
ABSTRACT Background This present systematic review and meta‐analysis aims to compare overall survival (OS), disease‐free survival (DFS), morbidity and mortality outcomes in patients undergoing colorectal first (CRf) versus liver first (Lf) resections with synchronous colorectal liver metastases.
Sofoklis Mavrantonis +3 more
wiley +1 more source
Neoadjuvant chemoradiotherapy vs. direct surgery for locally advanced esophageal cancer: a meta-analysis. [PDF]
Li L, Liu L, Yu C, Chen S.
europepmc +1 more source
ABSTRACT Background Learning curves in esophagectomy are often described in terms of procedural volume, but institutional maturation also reflects progressive standardization of reconstruction, operative choreography, and team‐based decision‐making.
Mayank Tripathi +6 more
wiley +1 more source

