Results 31 to 40 of about 92,115 (273)

Neoadjuvant nimotuzumab plus chemoradiotherapy compared to neoadjuvant chemoradiotherapy and neoadjuvant chemotherapy for locally advanced esophageal squamous cell carcinoma

Oncotarget, 2018
Neoadjuvant therapy improves long-term locoregional control and overall survival after surgical resection for esophageal cancer, and neoadjuvant chemotherapy (nCT) or neoadjuvant chemoradiotherapy (nCRT) are commonly used in clinical practice. Nimotuzumab is a humanized monoclonal antibody against epidermal growth factor receptor (EGFR), the efficacy ...
Chen, Yongshun, Wu, Xiaoyuan, Hao, Daxuan, Cheng, Xinyu, Zhang, Lei, Zhang, Yougai, Ke, Shaobo, Shi, Wei, He, Chunyu   +8 more
openaire   +3 more sources

The effects of cancer therapies on physical fitness before oesophagogastric cancer surgery: a prospective, blinded, multi-centre, observational, cohort study [version 1; peer review: 2 approved]

NIHR Open Research, 2021
Background: Neoadjuvant cancer treatment is associated with improved survival following major oesophagogastric cancer surgery. The impact of neoadjuvant chemo/chemoradiotherapy on physical fitness and operative outcomes is however unclear.
Lisa Loughney, Gareth Ambler, Thomas Owen, Michael G. Mythen, Denny Z.H. Levett, Gerard Danjoux, Jamie J. Kelly, Peter M.A. Calverley, Michael P.W. Grocott, Sandy Jack, Zachos Anastasiou, Malcolm A. West   +11 more
doaj   +1 more source

Neoadjuvant chemotherapy or chemoradiotherapy in head and neck cancer [PDF]

Indian Journal of Cancer, 2008
The multidisciplinary approach to treating squamous cell carcinoma of the head and neck is complex and evolving. Chemotherapy is increasingly being incorporated into the treatment of squamous cell carcinoma of the head and neck. Previously, radiotherapy following surgery was the standard approach to the treatment of loco regionally advanced resectable ...
Jain, Preetesh, Kumar, Prabhash, Pai, Vasanth Raghuvir, Parikh, Purvish Mahendra   +3 more
openaire   +2 more sources

A central review of histopathology reports after breast cancer neoadjuvant chemotherapy in the neo-tango trial [PDF]

, 2013
Background: Neo-tAnGo, a National Cancer Research Network (NCRN) multicentre randomised neoadjuvant chemotherapy trial in early breast cancer, enroled 831 patients in the United Kingdom.
K Walland, N Fenwick, M Iddawela, E Provenzano, Walland, K., Abraham, J. (Janet), Grier, Anna, L Hiller, J Abraham, A Grier, Fenwick, Nicola, Bowden, S. (Sarah), Iddawela, M., Caldas, C., H M Earl, R Champ, S Bowden, J Dunn, Vallier, A. -L., Champ, R., Earl, Helena M., C Caldas, Dunn, Janet A., Hiller, Louise, A-L Vallier, Provenzano, E.   +25 more
core   +2 more sources

Neoadjuvant sequential chemoradiotherapy versus radiotherapy alone for treatment of high-risk extremity soft tissue sarcoma: a single-institution experience [PDF]

, 2017
Aim of the study : Patients with large and high-grade extremity soft-tissue sarcoma are at significant risk for distant metastasis and sarcoma-related death.
Agaoglu, Fulya, Meltem Ekenel, Karabulut, Senem, Emin Darendeliler, Fulya Ağaoğlu, Darendeliler, Emin, Leyla Kılıç, Senem Karabulut, Ekenel, MELTEM, Kilic, Leyla   +9 more
core   +1 more source

Breast cancer: Monitoring response to neoadjuvant chemotherapy using Tc-99m sestamibi scintimammography [PDF]

, 2003
Background: Aim of the study was to assess the value of scintimammography using Tc-99m sestamibi in the evaluation of tumor response to neoadjuvant chemotherapy.
Sommer, H., Keßler, M., Tiling, R., Brinkbäumer, K., Hahn, K., Untch, M., Linke, R.   +6 more
core   +1 more source

Defining a positive circumferential resection margin in oesophageal cancer and its implications for adjuvant treatment [PDF]

, 2013
A positive circumferential resection margin (CRM) has been associated with a poorer prognosis in oesophageal and oesophagogastric junctional (OGJ) cancer. The College of American Pathologists defines the CRM as positive if tumour cells are present at the
Driscoll, P J, Paterson-Brown, S., Kamel, H. M., Phillips, H A, O'Neill, Robert, Stephens, Nathan A, Save, V   +6 more
core   +1 more source

Active surveillance of oesophageal cancer after response to neoadjuvant chemoradiotherapy: dysphagia is uncommon [PDF]

, 2023
BACKGROUND: Active surveillance is being investigated as an alternative to standard surgery after neoadjuvant chemoradiotherapy for oesophageal cancer.
Jurjen J Boonstra, Andries van der Linden, Ben M Eyck, J Jan B van Lanschot, Peter D Siersema, Wouter L Hazen, Wijnhoven, Bas P.L., Rutger Quispel, Holster, I. Lisanne, Maria J Valkema, Jolanda M van Dieren, Doukas, Michail, G Willemien Erkelens, Eyck, Ben M., Manon C W Spaander, Hazen, Wouter L., Erkelens, G. Willemien, Berend J van der Wilk, Bas P L Wijnhoven, Oostenbrug, Liekele E., Erik J Schoon, Sjoerd M Lagarde, Klaas van der Linde, Valkema, Maria J., Michail Doukas, I Lisanne Holster, Quispel, Rutger, van der Sluis, Pieter C., van Lanschot, J. Jan B., Spaander, Manon C.W., van Dieren, Jolanda M., Schoon, Erik J., Liekele E Oostenbrug, Siersema, Peter D., van der Linde, Klaas, van der Linden, Andries, Lagarde, Sjoerd M., van der Wilk, Berend J., Pieter C van der Sluis, Boonstra, Jurjen J.   +39 more
core   +3 more sources

Neoadjuvant Chemoradiotherapy for Esophageal Cancer: A Review of Meta‐Analyses [PDF]

World Journal of Surgery, 2009
AbstractBackgroundMost randomized controlled trials (RCTs) that have compared neoadjuvant chemoradiation followed by surgery with surgery alone for locally advanced esophageal cancer have shown no difference in survival between the two treatments. Meta‐analyses on neoadjuvant chemoradiation in esophageal cancer, however, are discordant.MethodsFor the ...
Wijnhoven, Bas, van Lanschot, Jan, Tilanus, Hugo, Steyerberg, Ewout, van der Gaast, Ate   +4 more
openaire   +2 more sources

Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus

, 2013
AIM: To assess tumour regression grade (TRG) and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS: Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal ...
Kelly, Jamie, Iveson, T., Underwood, T.J., Rees, Charlotte, Bailey, Ian, Bateman, Andrew R., Byrne, James, Sharland, Donna, Noble, Fergus, Bateman, Adrian C., Nolan, Luke   +10 more
core   +1 more source