Results 231 to 240 of about 2,703,409 (308)

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Tissue Clearing for Lymph Nodes: 3D Mapping of Nerves and the Immune Microenvironment

iNew Medicine, EarlyView.
ABSTRACT Lymph nodes (LNs) are central hubs of adaptive immunity and key relay sites for metastatic tumour cells. However, conventional two‐dimensional histology samples only a small fraction of each node, potentially missing micrometastases and multifocal involvement while obscuring long‐range spatial relationships among tumour deposits, immune ...
Guang‐Hong Su, Fei Wang, Ting‐Hong Wei, Rui Lu, Wen‐Jun Huang, Xiang Zhang, Ling Yin, Jun Li   +7 more
wiley   +1 more source

Clinical Decision-Making After Receptor Conversion Following Neoadjuvant Therapy in Breast Cancer: A Three-Strategy Framework. [PDF]

J Clin Med
Pogoda K, Czopowicz M, Olszewski W, Durzynska M, Wysocki PJ.   +4 more
europepmc   +1 more source

CSRP1 Drives Helicobacter pylori‐Associated Gastric Cancer Progression via IL‐6/JAK2/STAT3‐Mediated Epithelial–Mesenchymal Transition

iNew Medicine, EarlyView.
Helicobacter pylori infection‐associated chronic gastritis induces CSRP1 upregulation in gastric cancer cells. Elevated CSRP1 activates the IL‐6/JAK2/STAT3 signaling pathway by promoting IL‐6 expression, JAK2 phosphorylation, and STAT3 nuclear translocation.
Chao Li, Wanjing Chen, Yawei He, Yida Lu, Gang Yu, Ruqiong Wei, Raquel Alarcón Rodríguez, Zhengguang Wang   +7 more
wiley   +1 more source

Dynamic Changes in PD-L1, VEGF, and TILs Following Neoadjuvant Therapy in Residual Invasive Breast Cancer. [PDF]

Curr Issues Mol Biol
Bakula M, Rajc J, Kvolik Pavic A, Kvolik S.   +3 more
europepmc   +1 more source

Comparison of Continuous‐Time Random Walk and Fractional Order Calculus Diffusion Models for Preoperative Breast Lesion Characterization: Diagnosis, Biomarker Prediction and Molecular Subtyping

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Accurate preoperative characterization of breast lesions is important for individualized management. The conventional monoexponential (Mono) model has limited ability to capture the complex microstructure of lesions. Non‐Gaussian diffusion models, including continuous‐time random walk (CTRW) and fractional‐order calculus (FROC), may
Yimeng Cao, Shaomin Li, Zhexuan Yang, Xueyan Liu, Shifang Tan, Tian Ren, Wenjia Wang, Haiyang Li, Xingzhi Chen, Xin Zhao, Meiying Cheng   +10 more
wiley   +1 more source

Safety and Efficacy of Neoadjuvant Therapy in Cholangiocarcinoma: Protocol for a Systematic Review and Meta-Analysis. [PDF]

JMIR Res Protoc
Mandal S, Dhali A, Maji M, Venkatachalapathy SV, Khanna A, Gomez D, Arora A, Aithal G.   +7 more
europepmc   +1 more source

Prognostic Determinants of Overall Survival After Resection for Pancreatic Ductal Adenocarcinoma: A Consensus‐Based Conceptual Framework

Journal of Surgical Oncology, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis despite surgical resection, yet the prognostic literature remains fragmented across hundreds of single‐institution studies that vary in design, covariates, and analytical approaches.
Muhammad Maisam Ali, Kaleem S. Ahmed, Clayton T. Marcinak, Syed Ali Tayyeb Hasan, Anne D. Letocha, Noorain Ahmad, Haider bin Khalid, Kainat Fatima, Syed Nabeel Zafar   +8 more
wiley   +1 more source

Pathological assessment of tumour beds in breast excisions post-neoadjuvant therapy: a retrospective cohort study. [PDF]

Histopathology
Cheng A, Barnes P, Rayson D, Liwski C, Bethune G.   +4 more
europepmc   +1 more source

Timing Matters: A Meta‐Analysis of BREAST‐Q Administration in Tissue‐Expander and Implant‐Based Breast Reconstruction

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background BREAST‐Q is the most widely used patient‐reported outcome measure following breast reconstruction, yet no consensus exists on optimal timing or duration of administration. We analyzed BREAST‐Q follow‐up after implant‐based reconstruction, comparing direct‐to‐implant (DTI) and two‐stage tissue expander (TE), to determine how outcomes
Emanuella M. Brito, Isabel Bernal, Sean K. Park, Julia L. Armstrong, Natalia Correa, Anthony Pasarin, Anastasia Tousimis, Graham S. Schwarz, Martin I. Newman   +8 more
wiley   +1 more source