Results 41 to 50 of about 144,610 (311)

Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus

, 2013
AIM: To assess tumour regression grade (TRG) and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS: Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal ...
Kelly, Jamie, Iveson, T., Underwood, T.J., Rees, Charlotte, Bailey, Ian, Bateman, Andrew R., Byrne, James, Sharland, Donna, Noble, Fergus, Bateman, Adrian C., Nolan, Luke   +10 more
core   +1 more source

Preoperative Hormone Therapy in the Treatment of Breast Cancer: What Do We Know So Far?

Креативная хирургия и онкология, 2022
Breast cancer is the most common malignant disease in the world. One of the methods of treating breast cancer is neoadjuvant chemotherapy. Neoadjuvant chemotherapy (NCT) is now the standard of care for locally advanced breast cancer.
V. V. Vorotnikov, R. A. Pakhomova, A. V. Soinov, A. S. Gunina, I. V. Kopytich, M. G. Tsoi, S. A. Abdugafforov   +6 more
doaj   +1 more source

Neoadjuvant therapy for breast cancer [PDF]

Tumori Journal, 2019
Objective: To evaluate the frequency of neoadjuvant therapy (NT) in women with stage I–III breast cancer in Italy and whether it is influenced by biological characteristics, screening history, and geographic area.
Lucia Mangone, Pamela Mancuso, Giovanna Tagliabue, Rosa Angela Filiberti, Giuliano Carrozzi, Silvia Iacovacci, Walter Mazzucco, Rosario Tumino, Pamela Minicozzi, Milena Sant, Paolo Giorgi Rossi   +10 more
openaire   +2 more sources

Cancer nanomedicine in preoperative therapeutics: Nanotechnology-enabled neoadjuvant chemotherapy, radiotherapy, immunotherapy, and phototherapy

Bioactive Materials, 2023
Surgical resection remains a mainstay in the treatment of malignant solid tumors. However, the use of neoadjuvant treatments, including chemotherapy, radiotherapy, phototherapy, and immunotherapy, either alone or in combination, as a preoperative ...
Xiaogang Qu, Dong Zhou, Jianpu Lu, Duotian Qin, Jun Zhou, Hai-Jun Liu   +5 more
doaj   +1 more source

Real-world analysis of leuprorelin acetate microspheres-based neoadjuvant therapy for patients with high-risk prostate cancer

Frontiers in Oncology
ObjectiveBoennuokang® leuprorelin acetate microspheres show a certain efficacy in patients with prostate cancer, but its utilization as neoadjuvant therapy in patients with high-risk prostate cancer remains unclear.
Changde Fu, Jun Xin, Jinjin Lai, Xu Zeng, Yongnan Wang, Wei Zhang   +5 more
doaj   +1 more source

Tumor regression grading of gastrointestinal cancers after neoadjuvant therapy. [PDF]

, 2017
Neoadjuvant therapy has been successfully introduced in the treatment of locally advanced gastrointestinal malignancies, particularly esophageal, gastric, and rectal cancers.
Rupert Langer, Becker, Karen, Langer, Rupert, Karen Becker   +3 more
core   +1 more source

Lung Cancer Surgery after Neoadjuvant Immunotherapy

, 2021
In early-stage lung cancer, recurrences are observed even after curative resection. Neoadjuvant immunotherapy might be a promising approach to eliminate micrometastasis and to potentially reduce recurrence rates and improve survival.
Dirk Stefani, Kaid Darwiche, Clemens Aigner, Till Plönes, Martin Stuschke, Martin Schuler, Jan Viehof   +6 more
core   +1 more source

HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer

, 2013
Introduction: Recent data suggest that benefit from trastuzumab and chemotherapy might be related to expression of HER2 and estrogen receptor (ESR1). Therefore, we investigated HER2 and ESR1 mRNA levels in core biopsies of HER2-positive breast carcinomas
Jens Huober, Reinisch, Mattea, Sibylle Loibl, Silvia Darb-Esfahani, Michael Untch, Hans Tesch, Martin-Leo Hansmann, Jan C Brase, Knut Engels, Judith Prinzler, Keyur Mehta, Minckwitz, Gunter von, Brase, Jan C., Kronenwett, Ralf, Hansmann, Martin-Leo, Huober, Jens, Engels, Knut, Solbach, Christine, Tesch, Hans, Carsten Denkert, Denkert, Carsten, Gunter von Minckwitz, Bruno V Sinn, Loibl, Sibylle, Mattea Reinisch, Peter A Fasching, Sinn, Bruno V., Ralf Kronenwett, Christine Solbach, Prinzler, Judith, Mehta, Keyur, Fasching, Peter Andreas, Untch, Michael, Denkert, Carsten Michael, Darb-Esfahani, Silvia   +34 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

An open, observational clinical study of neoadjuvant therapy in resectable stage III non-small cell lung cancer

Frontiers in Oncology, 2023
BackgroundThis open, observational clinical study aimed to investigate the efficacy, safety and survival outcomes of neoadjuvant chemotherapy, neoadjuvant immunotherapy with(out) chemotherapy and neoadjuvant targeted therapy among resectable stage III ...
Yuwen Qi, Linping Gu, Jie Shen, Yaxian Yao, Yi Zhao, Shun Lu, Zhiwei Chen   +6 more
doaj   +1 more source