Results 91 to 100 of about 1,997,971 (386)

Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and Liver Fibrosis by Mediating TGF-β/Smad Signaling Pathway

Analytical Cellular Pathology
Background. Biliary atresia (BA) is a devastating congenital disease characterized by inflammation and progressive liver fibrosis. Activation of hepatic stellate cells (HSCs) plays a central role in the pathogenesis of hepatic fibrosis.
Guang Xu, Tidong Ma, Chonggao Zhou, Fan Zhao, Kun Peng, Bixiang Li   +5 more
doaj   +1 more source

Nanodiamond‐Infused Microgels for pH‐Tunable Rheology, Lubrication, and UV Protection

Advanced Functional Materials, EarlyView.
Microgels consisting of swollen polyacrylic acid polymer networks, impregnated with nanodiamonds provide protection from ultraviolet (UV) radiation harmful to human health. Nanodiamonds enable UV blockage and control of the rheology (flow) and lubrication (skin‐feel) of these microgel‐skincare‐mimics.
Pallav K. Jani, Sarvesh A. Nadkarni, Katherine J. Ernst, Barbara V. Farias, Chloe G. Hincher, Oluwatobi A. Ojuade, Yug C. Saraswat, Prottasha Sarker, Donald O. Freytes, Lilian C. Hsiao, Saad A. Khan   +10 more
wiley   +1 more source

Mesenchymal Stem Cell Derived Exosomes Alleviates Hirschsprung-Associated Enterocolitis by Inhibiting AKT Phosphorylation in Macrophages Through miR-223

Stem Cells International
Conclusion: Macrophages accumulate in colonic tissues during HAEC and inflammatory macrophages drive enterocyte death. MSCs derived exosomes reduce enterocyte death by suppressing AKT phosphorylation and IL-1β secretion via miR-223, and subsequently ...
Haosen Ji, Zheming Xu, Leiting Shen, Sisi Yang, Jingyi Jin, Chengjie Lyu, Yichao Ren, Yi Xiao, Yuebai Zhang, Shu Fang, Xiaoxia Zhao, Xiang Yan, Dengming Lai, Jinfa Tou   +13 more
doaj   +1 more source

Evaluation of glycerin suppository in prevention of neonatal jaundice in Besat Hospital in 2016-2017 [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان, 2019
Background and Aim: Neonatal jaundice is a common problem in the neonates which is caused by increased unconjugated bilirubin and can result in serious neurological side effects such as kerinictrus.
Mansouri M, Nouri B, Iri R
doaj  

Neonatal mortality and associated factors in the specialized neonatal care unit Asmara, Eritrea

BMC Public Health, 2020
BackgroundLimited knowledge on the magnitude of neonatal mortality and associated factors is hampering early intervention in African countries.Objective: To determine neonatal mortality and associated factors in the Specialized Neonatal Care Unit Asmara,
A. Andegiorgish, Mihreteab Andemariam, Sabela Temesghen, Liya Ogbai, Z. Ogbe, L. Zeng   +5 more
semanticscholar   +1 more source

Hypertension in the Neonate [PDF]

Pediatric Research, 1985
Blood pressure (BP) is low at birth. It increases with age, by about 1 mm Hg per day within the period of 3 to 8 days. It rises by about 1 mm Hg per week between ages 5 to 6 weeks. At a latter age, systolic BP is close to 95 +/- 10 mm Hg. Hypertension is a rare condition in the neonate, where it carries a high risk of cardiorespiratory failure and ...
openaire   +3 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Neonatal Septic Arthritis - A Case Report

Journal of Pediatric Emergency and Intensive Care Medicine, 2022
Neonatal septic arthritis is a rare condition, and yet it is an orthopaedic emergency due to the potential of devastating consequences. Signs and symptoms, laboratory test, and imaging studies might not always be typical. A prompt diagnosis and treatment
Kartini Ciatawi, Halim Ciatawi
doaj   +1 more source

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

Advanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Helping small babies survive: an evaluation of facility-based Kangaroo Mother Care implementation progress in Uganda

The Pan African Medical Journal, 2014
INTRODUCTION: Prematurity is the leading cause of newborn death in Uganda, accounting for 38% of the nation's 39,000 annual newborn deaths. Kangaroo mother care is a high-impact; cost-effective intervention that has been prioritized in policy in Uganda ...
Patrick Aliganyira, Kate Kerber, Karen Davy, Nathalie Gamache, Namaala Hanifah Sengendo, Anne-Marie Bergh   +5 more
doaj   +1 more source