Short-Term Neurodevelopmental Outcome in Term Neonates Treated with Phenobarbital versus Levetiracetam: A Single-Center Experience [PDF]
, 2019 BACKGROUND: Phenobarbital (PB) has been traditionally used as the first-line treatment for neonatal seizures. More recently, levetiracetam (LEV) has been increasingly used as a promising newer antiepileptic medication for treatment of seizures in ...
Barbagallo, M. +7 more
core +3 more sources
Silicon Nanowire Mats Enable Advanced Bioelectrical Recordings in Primary DRG Cell Cultures
Advanced Healthcare Materials, Volume 14, Issue 17, July 4, 2025.SiNW mat‐based MEA (NW_MEA) enables continuous intracellular recordings from neurons in primary rat DRG cell cultures, identifying C‐fiber nociceptors. Supported by an astrocyte feeder layer, SiNW mat promotes DRG neuron and glial cell growth, preserving in vivo‐like cell characteristics and allowing drug‐modulated activity monitoring.
Ivano Lucarini +12 more
wiley +1 more source
Hypertension in the Neonate [PDF]
Pediatric Research, 1985 Blood pressure (BP) is low at birth. It increases with age, by about 1 mm Hg per day within the period of 3 to 8 days. It rises by about 1 mm Hg per week between ages 5 to 6 weeks. At a latter age, systolic BP is close to 95 +/- 10 mm Hg. Hypertension is a rare condition in the neonate, where it carries a high risk of cardiorespiratory failure and ...
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Magnetic‐Driven Torque‐Induced Electrical Stimulation for Millisecond‐Scale Wireless Neuromodulation
Advanced Healthcare Materials, EarlyView.MagTIES is a wireless neuromodulation technique with millisecond precision. It employs magnetic‐driven torque from magnetite nanodiscs to activate piezoelectric nanoparticles, enabling precise temporal control of neuronal activity and brain oscillations using weak, low‐frequency magnetic fields.
Chao‐Chun Cheng +5 more
wiley +1 more source
Genotypic and Phenotypic Diversity of Herpes Simplex Virus 2 within the Infected Neonatal Population
mSphere, 2019 More than 14,000 neonates are infected with herpes simplex virus (HSV) annually. Approximately half display manifestations limited to the skin, eyes, or mouth (SEM disease).
Lisa N. Akhtar +9 more
doaj +1 more source
Mediation Analysis Supports a Causal Relationship between Maternal Hyperglycemia and Placental DNA Methylation Variations at the Leptin Gene Locus and Cord Blood Leptin Levels. [PDF]
, 2020 Changes in fetal DNA methylation (DNAm) of the leptin (LEP) gene have been associated with exposure to maternal hyperglycemia, but their links with childhood obesity risk are still unclear.
Bouchard, Luigi +8 more
core +1 more source
Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
Advanced Healthcare Materials, EarlyView.This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Health Technology Assessment, 2021 Background: The diagnosis of preterm labour is challenging. False-positive diagnoses are common and result in unnecessary, potentially harmful treatments (e.g.
Sarah J Stock +23 more
doaj +1 more source
MicroRNA-210 Suppresses Junction Proteins and Disrupts Blood-Brain Barrier Integrity in Neonatal Rat Hypoxic-Ischemic Brain Injury. [PDF]
, 2017 Cerebral edema, primarily caused by disruption of the blood-brain barrier (BBB), is one of the serious complications associated with brain injury in neonatal hypoxic-ischemic encephalopathy (HIE).
Dasgupta, Chiranjib +4 more
core +2 more sources
Pediatric Anesthesia, 2013 SummaryEffective management of procedural and postoperative pain in neonates is required to minimize acute physiological and behavioral distress and may also improve acute and long‐term outcomes. Painful stimuli activate nociceptive pathways, from the periphery to the cortex, in neonates and behavioral responses form the basis for validated pain ...
openaire +3 more sources