Results 51 to 60 of about 4,948,984 (299)

Māori whānau experiences of a neonatal intensive care unit: Waikato hospital [PDF]

open access: yes, 2009
This thesis topic emerged from my personal experience of having a premature baby in the Neonatal Intensive Care Unit (NICU) at Waikato hospital. My whānau and I felt like aliens; culturally inept, and totally alone during our time in the NICU.
Thompson, Keri
core  

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao   +7 more
wiley   +1 more source

Update on COVID-19 in the pediatric population at University Hospital of Oran. A retrospective study [PDF]

open access: yesBatna Journal of Medical Sciences
Introduction. The spread of the novel coronavirus SARS-CoV-2, discovered in China in January 2020, led to a pandemic in Algeria as early as February. Children and adolescents under the age of 18 were much more rarely affected than adults and account ...
Djamila-Djahida BATOUCHE   +9 more
doaj   +1 more source

Cultura de segurança do paciente em unidades de terapia intensiva neonatal [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2013.A cultura de segurança do paciente é discutida mundialmente sendo considerada um elemento essencial
Tomazoni, Andréia
core  

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

A Rare Case Report of Nosocomial Urosepsis due to Klebsiella pneumoniae in a Preterm Neonate Complicated by Acute Cystitis

open access: yesCase Reports in Infectious Diseases
Late-onset sepsis secondary to urinary tract infection in preterm infants is frequently underdiagnosed and rarely reported. Establishing this diagnosis remains challenging, as clinical manifestations are often nonspecific, inflammatory markers may be ...
Bormey Sim   +3 more
doaj   +1 more source

Circular RNA cZNF292 silence alleviates OGD/R-induced injury through up-regulation of miR-22 in rat neural stem cells (NSCs)

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2020
Background Hypoxic-ischaemic encephalopathy (HIE) is a prevailing severe brain damage disease in newborns, and caused by perinatal asphyxia cerebral ischaemia and reperfusion.
Yaqin Cao   +3 more
doaj   +1 more source

Gerência do cuidado de enfermagem: incorporando melhores práticas em uma unidade de terapia intensiva neonatal [PDF]

open access: yes, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2014.Este estudo trata da elaboração de um modelo que contempla o fenômeno das organizações das práticas de ...
Klock, Patricia
core  

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

open access: yesAdvanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang   +22 more
wiley   +1 more source

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