Results 71 to 80 of about 152,103 (313)

Troubling care in the neonatal intensive care unit

Geoforum, 2020
The neonatal intensive care unit (NICU) is a site of medical treatment for premature and critically ill infants. It is a space populated by medical teams and their patients, as well as parents and family. Each actor in this space negotiates providing and practicing care.
Naylor, Lindsay, Clarke-Sather, Abigail, Weber, Michael   +2 more
openaire   +2 more sources

Neonatal Resuscitation

, 2023
Background:Teamwork during neonatal resuscitation is essential. Situations arise quickly and unexpectedly and are highly stressful, requiring pediatric registered nurses (pRN) to respond effectively and in a structured manner. In Sweden, pRNs work in all
Ulrica Gustafsson, Wallström, Linda,, Linda Wallström, Ylva Thernström Blomqvist, Blomqvist, Ylva Thernstrom, Karlsson, Lina,, Blomqvist, Ylva Thernstrom,, Anders Broström, Broström, Anders, Broström, Anders,, Gustafsson, Ulrica,, Karlsson, Lina, Lina Karlsson, Gustafsson, Ulrica, Thernström Blomqvist, Ylva,, Wallstrom, Linda   +15 more
core   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

Understanding infant stress in neonatal and pediatric intensive care: a scoping review

Infants in intensive care environments encounter numerous stressors which may overlap or occur in close proximity. Recent literature suggests stressful encounters in the neonatal or early infant period are harmful to physiological, functional, and ...
Pintz, Christine, Zhou, Quiping Pearl, Hinds, Pamela S., Darcy-Mahoney, Ashley, Mastropietro, Christopher, Riley, Christine   +5 more
core   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

Peripheral perfusion index-reference range in healthy Portuguese term newborns

Journal of Pediatric and Neonatal Individualized Medicine, 2014
Introduction: Peripheral perfusion index (PPI) is a non-invasive numerical value of peripheral perfusion derived from a pulse oximeter signal. It has been suggested that PPI may be a valuable adjunct diagnostic tool to detect early clinically significant
Joana Jardim, Ruben Rocha, Gorett Silva, Hercília Guimarães   +3 more
doaj   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Melatonin Suppresses NLRP3 Inflammasome Activation via SIRT1-Mediated ETS1 Deacetylation to Attenuate LPS-Induced Pyroptosis in Alveolar Epithelial Cells

Journal of Inflammation Research
Fan He, Chunzi Liu, Yun Yu, Qiaofang Wang, Lin Li, Xiaoyun Chao, Liping Chen, Cong Yu Neonatal Intensive Care Unit, Jiangxi Provincial Children’s Hospital, Nanchang, Jiangxi, 330038, People’s Republic of ChinaCorrespondence: Liping Chen, Neonatal ...
He F, Liu C, Yu Y, Wang Q, Li L, Chao X, Chen L, Yu C   +7 more
doaj  

Integrated Neonatal Intensive Care: Intensive Care for Baby at the Mother’s Bedside

, 2018
The traditional model of the Neonatal Intensive Care Unit (NICU) has separated babies from their mothers after delivery to receive intensive care in a different unit.
Kubik, Gina
core